🤖 GLOBAL HEALTH OPTIMIZATION AGENT v3.0

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🧬 Genetic Analysis

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📊 Resource Allocation by Research Phase:

📚 Data Analysis

🧪 Experimental Design

🔬 Clinical Trials

💊 Treatment Development

Trial Search

Current Search Criteria:

Intervention: Combination of DMARDs

Found 74 matching trials

A Study to Compare Subcutaneous Versus Intravenous Administration of RoActemra/Actemra (Tocilizumab) in Participants With Moderate to Severe Active Rheumatoid Arthritis

PHASE3

This randomized, double-blind, parallel group study compares the efficacy a...

Status

Completed

Location

Multiple Locations

Start Date

2010-09

Trial ID

NCT01194414

Treatments Being Tested

tocilizumab SC tocilizumab IV placebo to tocilizumab SC placebo to tocilizumab IV Disease-modifying antirheumatic drugs (DMARDs)

Infliximab and Classic DMARDs in the Rheumatoid Arthritis Patients

A prospective, multi-centric, cohort study to observe the efficacy differen...

Status

Unknown

Location

The Second Xiangya Hospital of Central South University

Start Date

2013-08

Trial ID

NCT01915537

Treatments Being Tested

Infliximab group Classic DMARDs treatment group

A Study of Tocilizumab (RoActemra/Actemra) in Monotherapy or in Combination With Methotrexate or Other Non-Biologic DMARDs in Participants With Active Rheumatoid Arthritis and an Inadequate Response to Current Non-Biologic DMARD Therapy or the First Anti-TNF Biologic Agent

PHASE3

This open-label study will evaluate the efficacy and safety of tocilizumab ...

Status

Completed

Location

Aberdeen Royal Infirmary

Start Date

2014-03-04

Trial ID

NCT02046603

Treatments Being Tested

Tocilizumab DMARDs Oral Corticosteroids Methotrexate

Arthroscopic Synovectomy Combined With DMARDs in the Treatment of Refractory Elbow Rheumatoid Arthritis

N/A

Rheumatoid arthritis (RA) is an autoimmune disease characterized by chronic...

Status

Unknown

Location

Peking Univerisity Third Hospital

Start Date

2019-08-01

Trial ID

NCT04454034

Treatments Being Tested

arthroscopic synovectomy

Study of Safety and Efficacy of BCD-020 Comparing to MabThera in Patients With Rheumatoid Arthritis

PHASE3

The purpose of this study is to prove that efficacy, safety and immunogenic...

Status

Completed

Location

Gomel Regional Clinical Hospital

Start Date

2012-12

Trial ID

NCT01759030

Treatments Being Tested

Rituximab

Improvement of Hand Dysfunction by Arthritis in Systemic Sclerosis

N/A

Systemic sclerosis (SSc) is an orphan, multiorgan disease affecting the con...

Status

Unknown

Location

University of Ghent, Department of Rheumatology

Start Date

2013-04

Trial ID

NCT01834157

To Evaluate The Safety of SAR153191 (REGN88) and Tocilizumab Added to Other RA Drugs in Patients With RA Who Are Not Responding to or Intolerant of Anti-TNF Therapy (SARIL-RA-ASCERTAIN)

PHASE3

Primary Objective: To assess, in the same study, the safety of sarilumab a...

Status

Completed

Location

Investigational Site Number 840152

Start Date

2013-03

Trial ID

NCT01768572

Treatments Being Tested

sarilumab SAR153191 (REGN88)tocilizumab hydroxychloroquine methotrexate sulfasalazine leflunomide subcutaneous placebo intravenous placebo

Validation Study of RA-INF-Dx, a Multigene Molecular Test Used to Predict Non-Response to INfliximab Therapy

N/A

Study Design \& Objectives: Multi-centre, non-interventional, open-label, ...

Status

Terminated

Location

Location n°31

Start Date

2011-02

Trial ID

NCT01299545

A Phase III Study of BMS-188667 in Subjects With Active Rheumatoid Arthritis

PHASE3

The purpose of this clinical research study is to learn if abatacept is saf...

Status

Completed

Location

Local Institution

Start Date

2002-12

Trial ID

NCT00048932

Treatments Being Tested

Double-blind Abatacept Double-blind Placebo Open-label Abatacept

A Study of RoActemra/Actemra (Tocilizumab) in Combination With Methotrexate in Patients With Active Rheumatoid Arthritis Who Have an Inadequate Response to Non-biologic DMARDs

PHASE3

This multicenter, open-label, single arm study will assess the safety and e...

Status

Completed

Location

Multiple Locations

Start Date

2011-03

Trial ID

NCT01353859

Treatments Being Tested

tocilizumab [RoActemra/Actemra]methotrexate

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