Found 11 matching trials
A Phase 1 Study of AB521 Monotherapy and Combination Therapies in Renal Cell Carcinoma and Other Solid Tumors PHASE1 The purpose of this study is to evaluate the safety and tolerability of:
*...
Show More Learn More & Join Trial
Study of Casdatifan and Cabozantinib Versus Placebo and Cabozantinib in Patients With Advanced Clear Cell Renal Cell Carcinoma PHASE3 The purpose of the study is to evaluate the progression-free survival (PFS)...
Show More Learn More & Join Trial
A Study to Evaluate the Safety, Tolerability, and Efficacy of Pumitamig Alone or in Combination With Other Agents in Participants With Advanced Renal Cell Carcinoma (RCC) (ROSETTA RCC-208) PHASE1 The purpose of this study is to evaluate the safety, tolerability, and effi...
Show More Location
Local Institution - 0178
Learn More & Join Trial
Pre-NEOSHIFT-RCC: Neoadjuvant HIF-Inhibitor Immunotherapy in RCC PHASE2 The purpose of this study is to see whether the drug casdatifan is safe and...
Show More Location
Beth Israel Deaconess Medical Center
Learn More & Join Trial
A Bioequivalence Study Between Two Casdatifan Tablet Strengths and Food Effect Study of Casdatifan in Healthy Adult Participants PHASE1 The purpose of this study is to compare the single-dose pharmacokinetics (P...
Show More Learn More & Join Trial
Study to Investigate the Safety, Tolerability, and Pharmacokinetic Profile With Oral AB521 in Healthy Volunteers PHASE1 This study will evaluate the safety and tolerability, pharmacokinetic, and ...
Show More Location
Investigational Site
Learn More & Join Trial
Pilot Study of Casdatifan-Treated Refractory Renal Cell Carcinoma EARLY_PHASE1 This is a single-institution, pilot study of oral casdatifan, a selective H...
Show More Location
Vanderbilt University Medical Center
Learn More & Join Trial
Comparative PK Assessment Study of Casdatifan in Moderate Hepatically Impaired Participants Versus Matched Participants With Normal Hepatic Function PHASE1 The purpose of the study is to compare the single dose PK of casdatifan bet...
Show More Location
Multiple Locations
Learn More & Join Trial
Drug-Drug Interaction Study of Casdatifan in Healthy Adult Participants (ARC-29) PHASE1 The purpose of the study is to assess the effects of multiple doses of itra...
Show More Learn More & Join Trial
A Relative Bioavailability Study and Food Effect Study of AB521 in Healthy Adult Volunteers PHASE1 The primary purpose of this study is to compare the single-dose pharmacokin...
Show More Learn More & Join Trial