Found 16 matching trials
A Study to Investigate the Pharmacokinetics of Midazolam After Repeated Doses of Camizestrant (AZD9833) and to Investigate the Pharmacokinetics of Camizestrant When Administered Alone and in Combination With Carbamazepine in Healthy Post-Menopausal Female Participants PHASE1 This study will be conducted in order to determine the effect of repeated o...
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A Phase IIIb Study to Evaluate Camizestrant Plus Ribociclib in ER-positive, HER2-negative Advanced Breast Cancer PHASE3 The purpose of this study is to investigate the efficacy, safety, and toler...
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Study to Evaluate the Safety and Tolerability of Camizestrant in Combination With Atirmociclib in Women With Advanced Breast Cancer PHASE2 A study to investigate camizestrant in combination with atirmociclib in par...
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A Study to Investigate Efficacy and Safety With Oral AZD9833 Compared With Intramuscular Fulvestrant in Post-menopausal Women at Least 18 Years of Age With Advanced ER-positive HER2 Negative Breast Cancer PHASE2 This study is randomized, open-label, parallel-group, multicentre Phase 2 s...
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Rising ctDNA to Tailor Endocrine Therapy Switch in Patients With ER+/HER2- Metastatic Breast Cancer. PHASE3 Rationale:
In patients with metastatic breast cancer, fragments of tumor D...
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Study of AZD9833 Alone or in Combination in Women With Advanced Breast Cancer. PHASE1 A Phase 1 Dose Escalation and Expansion Study of AZD9833 Alone or in Combin...
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A Study to Assess the Pharmacokinetics of Camizestrant (AZD9833) When Administered Alone and in Combination With Itraconazole PHASE1 This study will be conducted in healthy post-menopausal female subjects to ...
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Study to Investigate Hepatic Impairment on PK, Safety, Tolerability of Camizestrant in Post-Menopausal Female Subjects PHASE1 This will be a Phase I, multicentre, single-dose, non-randomized, open-labe...
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An Adjuvant Endocrine-based Therapy Study of Camizestrant (AZD9833) in ER+/HER2- Early Breast Cancer (CAMBRIA-2) PHASE3 This is a Phase III open-label study to assess if camizestrant improves out...
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Phase III Study to Assess AZD9833+ CDK4/6 Inhibitor in HR+/HER2-MBC With Detectable ESR1m Before Progression (SERENA-6) PHASE3 The study is intended to show superiority of AZD9833 in combination with CD...
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