Found 28 matching trials
A Phase 1 Drug-drug Interaction Study in Healthy Volunteers PHASE1 This is an open-label, single-sequence, drug-drug interaction study in heal...
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Healthcare Discoveries, LLC d/b/a ICON Development Solutions
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A PHASE 1, OPEN-LABEL, CROSS-OVER, FIXED SEQUENCE STUDY TO EVALUATE THE EFFECT OF MULTIPLE DOSES OF DS-1971A ON THE SINGLE DOSE PHARMACOKINETICS OF PROBE SUBSTRATES FOR CYP2B6, CYP2C8, CYP2C9, CYP2C19 AND CYP3A4 ENZYMES IN HEALTHY MALE AND FEMALE SUBJECTS PHASE1 This is an open-label, cross-over, fixed-sequence study. All subjects will ...
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Multiple Locations
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Drug Interaction Study of ZYN002 Transdermal Gel and Probe Substrates PHASE1 This study is an open-label drug-drug interaction (DDI) study of ZYN002 tra...
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CMAX Clinical Research
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Study to Investigate the Effect of BMS-986142 on the Pharmacokinetics (PK) of Methotrexate and Probe Substrate Cocktail in Healthy Patients PHASE1 To study the Pharmacokinetics (PK) parameters of montelukast, flurbiprofen,...
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Multiple Locations
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A Study to Assess the Effect of BMS-986142 on Pharmacokinetics (PK) of Probe Substrates PHASE1 The study is being conducted to assess the effect of BMS-986142 on the sing...
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Ppd Development, Lp
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Licorice Botanical Dietary Supplements - Metabolism and Safety in Women PHASE1 Human safety studies will be carried out to test whether red clover botanic...
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University of Illinois at Chicago
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To Determine the Effect of CYP Induction Following Administration of Nirogacestat in Healthy Adult Male Participants PHASE1 This study will evaluate the effects of nirogacestat 100 mg twice daily (BI...
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ICON Martini Groningen CRU
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Phase 1, Open-label, Drug-drug Interaction Study to Assess Effect Between Radiprodil and the Co-administered Drugs. PHASE1 This is a Phase 1, open-label, 3-period study to determine radiprodil's pot...
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Nucleus Network Melbourne
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A Study to Evaluate the Effect of Oral Doses of JNJ-54175446 on the Inhibition of Cytochrome P450 CYP3A4, CYP2C9, CYP1A2 and CYP2D6 Activity and the Induction of CYP2B6 and CYP2C19 Activity Using a Multiple Probe Substrate Cocktail in Healthy Subjects PHASE1 The main purpose of this study is to determine the potential inhibitory/ind...
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Clinical Pharmacology Unit
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A Study in Healthy Volunteers to Evaluate the Drug-Drug Interaction Potential of CCX168 With Concomitant Medications PHASE1 The primary objective of this study will be to evaluate the drug-drug inter...
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