Found 0 matching trials
Hepatic Drug Biotransformation in Children With Obstructive Sleep Apnea
NAThe purpose of this research study is to determine the effect of chronic ni...
Location
University of Louisville
Impact of Acute and Chronic Inflammation on Cytochromes P450 Activity Measured With Dried Blood Spot
N/ACytochromes P450, main enzymes of drug metabolism, play a prominent role in...
Location
Geneva University Hospitals, HUG
Phenotyping of High Dose Rifampicin
PHASE1Higher doses of rifampicin as a means of more efficient use of this pivotal...
Pharmacokinetic Study to Characterize Phenotyping Metrics of the "Basel" Cocktail After CYP Induction or Inhibition
PHASE1The purpose of this study is to assess how the pharmacokinetic profiles of ...
Location
Phase I Research Unit, University Hospital
Endobiotics for Phenotyping of Human Cytochrome P450 Enzymes
NACYP2D6 metabolizes \~25% of all marketed drugs. There is an important varia...
The Effect of a Peroxisome Proliferator-activated Receptor (PPAR) Alpha Agonist on Cytochrome P450 (CYP) Monooxygenase Activity in Humans
PHASE4The hypothesis is to test to see if the drug fenofibrate will increase impo...
Location
Vanderbilt University
rhGH Therapy on Hepatic Drug Metabolism
N/AThe purpose of the study is to understand the effect of rhGH therapy on hep...
Location
University of California at San Diego
Genetic Study of CYP2D6 Enzyme and Therapeutic Drug Monitoring of Tamoxifen
N/AAim of work:
1. To estimate the frequency of Cyp2D6\*1 and \*4 alleles in ...
Location
Multiple Locations
Identification of New Tools for Predicting Natural Metabolic Performance of the Liver
PHASE1The objective of this clinical trial is to identify endogenous compounds (s...
Location
The Geneva University Hospitals (HUG)