Found 5 matching trials
Positron Emission Tomography (PET) Trial to Evaluate Target Occupancy of CVL-354 at Kappa and Mu Opioid Receptors in Brain Following Oral Dosing
PHASE1The primary purpose of this study is to assess the target occupancy at kapp...
Location
New Haven, Connecticut
A Single Dose Study to Assess Adverse Events and How Oral Icalcaprant Moves Through the Body in Healthy Adult Japanese and Han Chinese Participants
PHASE1This study will assess the pharmacokinetics, safety, and tolerability of ic...
Location
Anaheim Clinical Trials, LLC /ID# 271323
A Study to Assess Change in How Oral Icalcaprant With Itraconazole Moves Through the Body in Healthy Adult Participants
PHASE1This study is to assess the change of itraconazole, a strong CYP3A inhibito...
Location
Acpru /Id# 271617
A Study to Assess Adverse Events and Change in Disease Activity of Oral Icalcaprant in Adult Participants With Bipolar I or II Disorder
PHASE2Bipolar disorder is a severe chronic mood disorder that affects up to 4% of...
Location
University of Alabama - Huntsville Regional Medical Campus /ID# 272951
A Single and Multiple Ascending Dose Trial of CVL-354 in Healthy Participants
PHASE1This is a 2-part, double-blind, randomized, placebo-controlled, first-in-hu...
Location
Labcorp Drug Development