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A Phase 1/2 Study of Intravenous Gene Transfer With an AAV9 Vector Expressing Human Beta-galactosidase in Type I and Type II GM1 Gangliosidosis PHASE1 Background:
GM1 gangliosidosis is a disorder that destroys nerve cells. It...
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National Institutes of Health Clinical Center
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Genetic and Molecular Characterization of Nervous System Lesions N/A Primary and secondary brain tumors, the leading cause of death from cancer ...
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Service de Neurochirurgie - Hôpital de la Pitié Salpêtrière
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Testing the Safety of Anti-Cancer Drug, CX-5461 (Pidnarulex), in Treating Lymphoma With Specific Changes in the MYC Gene PHASE1 This phase Ib/II trial tests the safety, side effects, best dose and how we...
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UCI Health - Chao Family Comprehensive Cancer Center and Ambulatory Care
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Diagnostic of D-lactate in Cerebrospinal Fluid Level in Patients With Suspected Ventriculostomy-related Meningitis NA The TOTEM study is a single-center study designed to evaluate the performan...
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Toulouse Hospital
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Natural History Study of and Genetic Modifiers in Spinocerebellar Ataxias N/A Spinocerebellar ataxias (SCA) are genetic neurological diseases that cause ...
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University of California Los Angeles
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Pentostatin, Cyclophosphamide, Rituximab, and Mitoxantrone in Treating Patients With Chronic Lymphocytic Leukemia or Other Low-Grade B-Cell Cancer PHASE1 RATIONALE: Pentostatin may stop the growth of cancer cells by blocking some...
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Memorial Sloan-Kettering Cancer Center
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FH-FOLR1 Chimeric Antigen Receptor T Cell Therapy for Treating Pediatric Patients With Relapsed or Refractory Acute Myeloid Leukemia PHASE1 This phase I trial tests the safety, side effects, and best dose of FH-FOLR...
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Fred Hutch/University of Washington/Seattle Children's Cancer Consortium
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Medication Combinations of Dasatinib, Quercetin, Fisetin, Temozolomide, LMP744, and Autologous TLPO Vaccine for the Treatment of Previously Treated Glioma With Residual Disease EARLY_PHASE1 This early phase I trial tests the safety, side effects and how well medica...
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Mayo Clinic in Rochester
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Regulation of Lipid Metabolism in Autoimmune Disease: Multiple Sclerosis N/A The aim of this research is to understand how lipids such as cholesterol af...
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University College London Hospitals NHS Foundation Trust
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Intrathecal Dual Checkpoint Inhibitor (PD-1 and CTLA-4) in Combination With Pemetrexed for Leptomeningeal Metastasis PHASE1 This phase I/II study is to evaluate the recommended dose, safety, feasibil...
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Active Not Recruiting
Location
Aerospace Center Hospital, Peking University Aerospace School of Clinical Medicine
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