Found 70 matching trials
Use of Thalidomide, Lenalidomide, Carfilzomib, Bortezomib and Vorinostat in the Initial Treatment of Newly Diagnosed Multiple Myeloma Patients
PHASE3The purpose of this study is to compare a standard chemotherapy regimen of ...
Location
112 sites UK wide
Treatments Being Tested
Induction (intensive pathway) - cyclophosphamide, lenalidomide, & dexamethasone (CRD) regimenInduction (intensive pathway) - cyclophosphamide, thalidomide, & dexamethasone (CTD) regimenInduction (intensive pathway) - carfilzomib, cyclophosphamide, lenalidomide, & dexamethasone (CCRD) regimenInduction (non-intensive pathway) - cyclophosphamide, lenalidomide, & dexamethasone attenuated (CRDa) regimenInduction (non-intensive pathway) - cyclophosphamide, thalidomide, & dexamethasone attenuated (CTDa) regimenConsolidation (intensive & non-intensive pathways) - bortezomib, cyclophosphamide, & dexamethasone (VCD) regimenMaintenance (intensive & non-intensive pathways) - lenalidomide maintenanceMaintenance (intensive & non-intensive pathways - protocol v5.0 only) - lenalidomide plus vorinostat maintenanceHigh dose melphalan therapy and autologous stem cell transplant (intensive pathway only) Safety and Efficacy of rAAV2tYF-GRK1-RPGR in Subjects With X-linked Retinitis Pigmentosa Caused by RPGR Mutations
PHASE1This study will evaluate the safety and efficacy of a recombinant adeno-ass...
Status
Active Not Recruiting
Time Restricted Eating in Childhood Obesity (TRECO)
NAThe goal of this clinical trial is to learn if time-restricted eating (TRE)...
Location
Children's Hopital of Soochow University
CRD vs. Met in Patients With Obese PCOS Infertility
NAPolycystic ovary syndrome (PCOS) is a common gynecological endocrine diseas...
Location
Shanghai First Maternity and Infant Hospital
A Study of AAV5-hRKp.RPGR for the Treatment of Japanese Participants With X-linked Retinitis Pigmentosa
PHASE3The purpose of the study is to assess the safety and tolerability of bilate...
Status
Active Not Recruiting
Location
National Hospital Organization Tokyo Medical Center
Study to Evaluate ACDN-01 in ABCA4-related Stargardt Retinopathy (STELLAR)
PHASE1This study is an open-label, single ascending dose clinical trial in partic...
Location
University of San Francisco
Follow-up Gene Therapy Trial for the Treatment of X-linked Retinitis Pigmentosa Associated With Variants in the RPGR Gene
PHASE3A clinical trial of AAV5-hRKp.RPGR vector for participants with X-linked re...
Status
Active Not Recruiting
Location
Shiley Eye Institute Jacobs Retina Center
Comparing Centre-based, Remotely Supervised, and Self-administered STS Tests in Individuals With CRD
NADespite evidence on the psychometric properties of sit-to-stand (STS) tests...
Location
West Park Healthcare Centre
Gene Therapy for X-linked Retinitis Pigmentosa (XLRP) - Retinitis Pigmentosa GTPase Regulator (RPGR)
PHASE1Phase 1 of the study is a dose escalation of the subretinal administration ...
Location
Massachusetts Eye and Ear Institute
Cognitive Reappraisal Training for Borderline Personality (BPD)
NAPrevious work by the group convinced the researchers to pursue development ...
Location
Icahn School of Medicine at Mount Sinai