Found 10 matching trials
DEC-205/NY-ESO-1 Fusion Protein CDX-1401and Decitabine in Treating Patients With Myelodysplastic Syndrome or Acute Myeloid Leukemia PHASE1 This phase I trial studies the side effects and immune response to DEC-205/...
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Roswell Park Cancer Institute
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DEC-205/NY-ESO-1 Fusion Protein CDX-1401, Poly ICLC, Decitabine, and Nivolumab in Treating Patients With Myelodysplastic Syndrome or Acute Myeloid Leukemia PHASE1 This phase I trial studies the side effects of DEC-205/NY-ESO-1 fusion prot...
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Roswell Park Cancer Institute
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A Vaccine (CDX-1401) With or Without a Biologic Drug (CDX-301) for the Treatment of Patients With Stage IIB-IV Melanoma PHASE2 This phase II trial studies the effect of a vaccine called CDX-1401 given w...
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University of Chicago Comprehensive Cancer Center
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A Trial of CDX-1401 in Combination With Poly-ICLC and Pembrolizumab, in Previously Treated Advanced Solid Tumor Patients PHASE1 This study will look at the safety of the combination of three drugs (CDX-1...
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Multiple Locations
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Phase 2 Study of MPDL3280A Combined With CDX-1401 in NY-ESO 1 (+) IIIB, IV or Recurrent Non-Small Cell Lung Cancer PHASE2 The primary purpose of this study is to look at effects, good or bad, of co...
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A Study of CDX-1401 in Patients With Malignancies Known to Express NY-ESO-1 PHASE1 The main purpose of this study is to examine the safety and tolerability of...
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Yale Comprehensive Cancer Center
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Vaccine Therapy With or Without Sirolimus in Treating Patients With NY-ESO-1 Expressing Solid Tumors PHASE1 This phase I trial studies the side effects and best schedule of vaccine th...
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Roswell Park Cancer Institute
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A Study of Varlilumab (Anti-CD27) and Ipilimumab and CDX-1401 in Patients With Unresectable Stage III or IV Melanoma PHASE1 This is a study to determine the clinical benefit (how well the drug works)...
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California Pacific Medical Center Research Institute
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Atezolizumab, Guadecitabine, and CDX-1401 Vaccine in Treating Patients With Recurrent Ovarian, Fallopian Tube, or Primary Peritoneal Cancer PHASE1 This randomized phase I/IIb trial studies side effects and best dose of ate...
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Banner University Medical Center - Tucson
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DEC-205/NY-ESO-1 Fusion Protein CDX-1401, Poly ICLC, and IDO1 Inhibitor INCB024360 in Treating Patients With Ovarian, Fallopian Tube, or Primary Peritoneal Cancer in Remission PHASE1 This partially randomized phase I/IIb trial studies the side effects and be...
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Roswell Park Cancer Institute
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