Found 12 matching trials
Personalized TCR-T: Study of Adoptively Transferred T-cell Receptor Gene-engineered T Cells (TCR-T) PHASE1 This is a phase I/Ib study of adoptively transferred T-cell receptor gene-e...
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Active Not Recruiting
Location
Providence Portland Medical Center
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Immunologic Effects of CDX-301 and CDX-1140 in Resectable Pancreatic Cancer Patients PHASE2 The central hypothesis is that the addition of CDX-301 to CDX-1140 radicall...
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Washington University School of Medicine
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FLT3 Ligand, CD40 Agonist Antibody, and Stereotactic Radiotherapy PHASE1 The purpose of this study is to test a new way of treating the most common ...
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Albert Einstein College of Medicine
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CD40 Agonist, Flt3 Ligand, and Chemotherapy in HER2 Negative Breast Cancer PHASE1 This research study is being done to find out if the immunotherapy drugs ca...
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University of Chicago Comprehensive Cancer Center
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A Study of CDX-1140 (CD40) as Monotherapy or in Combination in Patients With Advanced Malignancies PHASE1 This is a study to determine the maximum tolerated dose (MTD) for CDX-1140 ...
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HonorHealth Research Insititute
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In Situ Immunomodulation With CDX-301, Radiation Therapy, CDX-1140 and Poly-ICLC in Patients w/ Unresectable and Metastatic Solid Tumors PHASE1 This phase I trial evaluates the safety and effectiveness of in situ immuno...
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Active Not Recruiting
Location
Los Angeles General Medical Center
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Testing Whether Cemiplimab (REGN2810) Plus CDX-1140 Given Prior to Surgery Are Better Than Cemiplimab (REGN2810) Alone in Patients With Stage III-IV Head and Neck Cancer PHASE2 This phase II trial compares the effectiveness of cemiplimab with CDX-1140 ...
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UCI Health - Chao Family Comprehensive Cancer Center and Ambulatory Care
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A Maintenance Therapy Study of Odetiglucan With CDX-1140 in Patients With Metastatic Pancreatic Ductal Adenocarcinoma PHASE1 The primary objective of this maintenance therapy study is to identify the ...
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HonorHealth Research Institute
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A Study of CDX-1140, a CD40 Agonist, in Combination With Capecitabine and Oxaliplatin (CAPOX) and Keytruda in Subjects With Biliary Tract Carcinoma (BTC) PHASE1 Background:
Biliary tract carcinoma (BTC) is cancer of the slender tubes t...
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National Institutes of Health Clinical Center
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Pembrolizumab Combined With Bevacizumab With or Without Agonist Anti-CD40 CDX-1140 for the Treatment of Patients With Recurrent Ovarian Cancer PHASE2 This phase II trial tests whether pembrolizumab combined with bevacizumab w...
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Roswell Park Cancer Institute
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