Found 34 matching trials
Autologous CD8+ and CD4+ Transgenic T Cells Expressing High Affinity KRASG12V Mutation-Specific T Cell Receptors (FH-A11KRASG12V-TCR) in Treating Patients With Metastatic Solid Tumor Cancers With KRAS G12V Mutations PHASE1 This phase I trial studies the side effects and best dose of autologous CD8...
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Fred Hutch/University of Washington Cancer Consortium
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Testing Drug Treatments After CAR T-cell Therapy in Patients With Relapsed/Refractory Diffuse Large B-cell Lymphoma PHASE2 This phase II trial tests whether mosunetuzumab and/or polatuzumab vedotin ...
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Banner University Medical Center - Tucson
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Nemtabrutinib and Lisocabtagene Maraleucel for the Treatment of Relapsed/Refractory Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma PHASE2 This phase II trial studies how well the addition of nemtabrutinib to lisoc...
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Fred Hutch/University of Washington Cancer Consortium
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Lisocabtagene Maraleucel, Nivolumab and Ibrutinib for the Treatment of Richter's Transformation PHASE2 This phase II trial tests how well adding lisocabtagene maraleucel (liso-ce...
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Active Not Recruiting
Location
City of Hope Medical Center
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A Phase 1/2 Study in Patients With HPV16+ Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma and Other Cancers PHASE1 This is a First in Human (FIH) Phase I/II, multinational, multicenter, open...
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O'Neal Comprehensive Cancer Center at UAB
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Study to Evaluate CD8 PET Imaging as a Marker of Immune Response to Stereotactic Body Radiation Therapy (ELIXR) PHASE1 "This phase I trial investigates the effect of radiation therapy on the imm...
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City of Hope Medical Center
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A Clinical Study of MK-8294 in Participants With Advanced Solid Tumors (MK-8294-001) PHASE1 MK-8294, the study medicine, is a type of targeted therapy designed to trea...
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Northwestern University ( Site 0101)
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⁸⁹Zr-Df-IAB22M2C (CD8 PET Tracer) for PET/CT in Patients With Metastatic Solid Tumors PHASE2 The purpose of this study is to evaluate the safety of repeat doses ⁸⁹Zr-Df...
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University of Alabama-Birmingham Hospital
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PICSTAT Pilot Study for CD8 PET/CT-Guided Lifileucel Treatment in Advanced Melanoma EARLY_PHASE1 This prospective, single-center pilot study is being performed to find out ...
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Abramson Cancer Center of the University of Pennsylvania
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A First-in-human Study to Evaluate the Safety and Tolerability of AZD8853 in Participants With Selected Advanced/Metastatic Solid Tumours PHASE1 A Phase I/IIa First-in-human, Open-label Study to Evaluate the Safety, Phar...
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