Found 71 matching trials
Safety and Efficacy Study of Flebogamma 5% DIF IGIV in Pediatric Subjects PHASE4 This is a multi-center, open-label study to assess the efficacy and safety ...
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University of South Florida
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CD40L Antagonism in Rheumatoid Arthritis (RA) PHASE2 The primary objective is to determine if the addition of a 12-week course o...
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University of California San Francisco School of Medicine: Lupus Clinic and Rheumatology Clinical Research Center
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Safety, Tolerability, and Efficacy of Immunomodulation With A Monoclonal Antibody Against CD40L in Combination With Transplanted Islet Cells in Adults With Brittle Type 1 Diabetes Mellitus (T1D) PHASE1 Tegoprubart (AT-1501) is a monoclonal antibody. Antibodies are Y-shaped pro...
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Active Not Recruiting
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University of Chicago
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Effects of Clopidogrel on Blood Pressure PHASE4 Context: Soluble CD40 ligand (sCD40L) released from activated platelets ind...
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University of Cologne
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A Phase I/II Trial Investigating LOAd703 in Combination With Atezolizumab in Malignant Melanoma PHASE1 This study aims to evaluate safety and effect of combining an oncolytic ade...
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Cedars-Sinai Medical Center, The Angeles Clinic and Research Institute
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Studies of Disorders in Antibody Production and Related Primary Immunodeficiency States N/A This study investigates gene abnormalities in Primary Immune Deficiency(PID...
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National Institutes of Health Clinical Center, 9000 Rockville Pike
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Treating High Risk Leukemia With CD40 Ligand & IL-2 Gene Modified Tumor Vaccine PHASE1 This research study is to determine the safety and dosage of special cells ...
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Texas Children's Hospital GCRC
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Universal Granulocyte Macrophage-colony Stimulating Factor (GM-CSF)-Producing and GM.CD40L for Autologous Tumor Vaccine in Mantle Cell Lymphoma PHASE2 RATIONALE: Vaccines made from gene-modified cells and a person's cancer cel...
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H. Lee Moffitt Cancer Center and Research Institute
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Safety Study on AdCD40L Gene Therapy for Bladder Cancer PHASE1 The study objective is to evaluate the feasibility of three instillations o...
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Uppsala University Hospital
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Unrelated Hematopoietic Stem Cell Transplantation(HSCT) for Genetic Diseases of Blood Cells PHASE1 This is a clinical trial of bone marrow transplantation for patients with t...
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Children Hospital Los Angeles
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