Found 52 matching trials
First-in-human Trial With Single-dose C5a-neutralizing AON-D21 in Healthy Male Subjects PHASE1 The main purpose of this study is to evaluate safety, tolerability, pharmac...
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Zilucoplan® in Improving Oxygenation, Short-, Longterm Outcome of COVID19 Patients With Acute Hypoxic Respiratory Failure PHASE2 The study is a randomized controlled, open-label trial comparing subcutaneo...
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Transcriptome and Metabolic Analyses of CHAPLE Disease N/A CHAPLE syndrome (complement hyperactivation, angiopathic thrombosis, protei...
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Marmara University
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This is a 96-week, Multicenter Study in Patients With Neovascular AMD That Evaluates OCUL101 for Efficacy, Safety, Durability, and Pharmacokinetics, Comparing it With Another Treatment. The Study Will be Conducted in Two Parts, Part A and Part B. PHASE2 Oculgen has begun a study of an investigational drug called OCUL101 as a po...
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Multiple Locations
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Evaluation of Interleukine 6 (and Other Cytokines and Inflammatory Markers) in COVID-19 Patients With a Systemic Inflammatory Response Syndrome NA In patients infected by the SARS-Cov-2 Coronavirus a severely progressive d...
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A Study to Evaluate the Pharmacokinetics of Avacopan (CCX168) in Participants With Mild or Moderate Hepatic Impairment PHASE1 The primary objective of this study will be to evaluate the pharmacokinetic...
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Clinical Pharmacology of Miami, Inc.
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Coversin in Paroxysmal Nocturnal Haemoglobinuria (PNH) PHASE2 Coversin in Paroxysmal Nocturnal Haemoglobinuria (PNH) in patients with res...
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Dr Saskia Langemeijer
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Study to Evaluate the Efficacy and Safety of APL-2 in Patients With Paroxysmal Nocturnal Hemoglobinuria (PNH) PHASE3 Evaluation of the Efficacy and Safety of APL-2 in Patients with Paroxysmal ...
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University of Southern California
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The Effect of Some Drugs Used in Treatment of Vasculitis on the Complement System in Children PHASE3 Vasculitis denotes affection of small to medium sized vessels by polyangiti...
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Assiut University Pediatric Hospital
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New Markers for Diagnosis of Prosthetic Infections N/A Implant infections are among the most dramatic complications in orthopaedic...
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IRCCS Istituto Ortopedico Galeazzi
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