Found 48 matching trials
A Study to Evaluate the Safety and Effect of Escalating Doses of CINRYZE PHASE4 The objectives of the study were:
1. To assess the safety and tolerability...
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Allergy, Asthma and Immunology Associates
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A Study to Evaluate the Safety and Pharmacokinetics of Two Formulations of C1-esterase Inhibitor PHASE1 A new formulation of Berinert (CSL830) is being investigated for the manage...
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Efficacy and Safety of Human Plasma-derived C1-esterase Inhibitor as add-on to Standard of Care for the Treatment of Refractory Antibody Mediated Rejection (AMR) in Adult Renal Transplant Recipients PHASE3 This is a double-blind, randomized-withdrawal, placebo-controlled study in ...
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University of Alabama Hospital (at Birmingham)
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C1 Esterase Inhibitor (C1INH-nf) for the Prevention of Acute Hereditary Angioedema (HAE) Attacks PHASE3 The study objective was to determine the safety and efficacy of C1INH-nf fo...
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Allergy and Immunology Associates
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A Pilot Study to Evaluate the Use of C1 Esterase Inhibitor (Human) in Patients With Acute Antibody-Mediated Rejection PHASE2 The purpose of this research study is to evaluate the safety, effect, and p...
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ViroPharma Investigative Site
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A Study to Evaluate the Long-term Clinical Safety and Efficacy of Subcutaneously Administered C1-esterase Inhibitor in the Prevention of Hereditary Angioedema PHASE3 The aim of this study is to assess the long-term safety of C1-esterase inhi...
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In Vivo Effects of C1-esterase Inhibitor on the Innate Immune Response During Human Endotoxemia - VECTOR II PHASE3 Excessive inflammation is associated with tissue damage caused by over-acti...
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Radboud University
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C1INH Inhibitor Preoperative and Post Kidney Transplant to Prevent DGF & IRI PHASE1 The use of C1INH (Berinert) in patients receiving deceased donor kidney tra...
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Cedars-Sinai Medical Center
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Safety and Efficacy Study of CINRYZE for Prevention of Angioedema Attacks in Children Ages 6-11 With Hereditary Angioedema PHASE3 Primary Objective - To assess the relative efficacy of two dose levels of C...
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Asthma and Allergy Associates, P.C
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Phase 1 Study to Assess the Safety, Tolerability, and Pharmacokinetics of Recombinant Human C1 Esterase Inhibitor in Healthy Adult Subjects PHASE1 This trial is looking to gain information about the safety and tolerability...
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Clinical Pharmacology of Miami
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