Autologous CD8+ and CD4+ Transgenic T Cells Expressing High Affinity KRASG12V Mutation-Specific T Cell Receptors (FH-A11KRASG12V-TCR) in Treating Patients With Metastatic Solid Tumor Cancers With KRAS G12V Mutations
PHASE1
This phase I trial studies the side effects and best dose of autologous CD8...
Status
Recruiting
Location
Fred Hutch/University of Washington Cancer Consortium
A Study of Imatinib Versus Nilotinib in Adult Patients With Newly Diagnosed Philadelphia Chromosome Positive (Ph+) Chronic Myelogenous Leukemia in Chronic Phase (CML-CP)
PHASE3
In this study, the efficacy and safety of two nilotinib doses, 300 mg twice...
Status
Completed
Location
University of California at Los Angeles Dept. of Hematology Clinic
Genetically Engineered Cells (BAFFR-CAR T Cells) for the Treatment of Relapsed or Refractory B-cell Acute Lymphoblastic Leukemia and B-cell Lymphoblastic Lymphoma
PHASE1
This phase I trial tests the safety and side effects of B-cell activating f...
Autologous T Cells Lentivirally Transduced to Express L1CAM-Specific Chimeric Antigen Receptors in Treating Patients With Locally Advanced and Unresectable or Metastatic Small Cell Neuroendocrine Prostate Cancer
PHASE1
This phase I trial studies the side effects and best dose of autologous CD8...
Status
Withdrawn
Location
Fred Hutch/University of Washington Cancer Consortium
Combination Chemotherapy With or Without Blinatumomab in Treating Patients With Newly Diagnosed BCR-ABL-Negative B Lineage Acute Lymphoblastic Leukemia
PHASE3
This randomized phase III trial studies combination chemotherapy with blina...