Found 22 matching trials
Targeting ATR in Soft-tissue Sarcomas PHASE2 Multicenter, prospective, open-labeled, 2-arm, non-comparative randomized p...
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Institut Bergonié
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Avelumab and M6620 for the Treatment of DDR Deficient Metastatic or Unresectable Solid Tumors PHASE1 This phase I/II trial studies the side effects and best dose of avelumab wi...
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Active Not Recruiting
Location
M D Anderson Cancer Center
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Carboplatin, Gemcitabine Hydrochloride, and Berzosertib in Treating Patients With Recurrent and Metastatic Ovarian, Primary Peritoneal, or Fallopian Tube Cancer PHASE1 This phase I trial studies the side effects and best dose of gemcitabine hy...
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Active Not Recruiting
Location
Mayo Clinic Hospital in Arizona
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Gemcitabine Hydrochloride Alone or With M6620 in Treating Patients With Recurrent Ovarian, Primary Peritoneal, or Fallopian Tube Cancer PHASE2 This randomized phase II trial studies how well ATR kinase inhibitor M6620 ...
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Active Not Recruiting
Location
Mayo Clinic Hospital in Arizona
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Berzosertib Human Mass Balance Study (DDRiver Solid Tumors 208) PHASE1 The study was conducted in two periods, Period 1 (mass balance) and Period ...
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Magyar Honvédség Egészségügyi Központ, Podmaniczky utcai telephely, Onkológiai Osztály
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Cisplatin and Gemcitabine Hydrochloride With or Without Berzosertib in Treating Patients With Metastatic Urothelial Cancer PHASE2 This phase II trial studies how well cisplatin and gemcitabine hydrochlorid...
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Mayo Clinic Hospital in Arizona
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ATRi Transition Rollover Study PHASE1 The main purpose of the study was to monitor the safety of participant rece...
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Royal Marsden NHS Foundation Trust
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M6620 First in Human Study PHASE1 An Open-Label, First-in-Human Study of the Safety, Tolerability, and Pharma...
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Mayo Clinic Arizona
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Trial of Topotecan With VX-970 (M6620), an ATR Kinase Inhibitor, in Small Cell Cancers and Extrapulmonary Small Cell Cancers PHASE1 Background:
Chemotherapy damages cancer cell deoxyribonucleic acid (DNA) s...
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National Institutes of Health Clinical Center, 9000 Rockville Pike
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Berzosertib and Irinotecan in Treating Patients With Progressive, Metastatic, or Unresectable TP53 Mutant Gastric or Gastroesophageal Junction Cancer PHASE2 This phase II trial studies the how well berzosertib and irinotecan work in...
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Active Not Recruiting
Location
City of Hope Comprehensive Cancer Center
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