Found 18 matching trials
Testing BVD-523FB (Ulixertinib) as Potentially Targeted Treatment in Cancers With Genetic Changes (MATCH - Subprotocol Z1L) PHASE2 This phase II MATCH treatment trial tests how well BVD-523FB (ulixertinib) ...
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ECOG-ACRIN Cancer Research Group
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Phase 1/2 Study of the ERK1/2 Inhibitor BVD-523 in Patients With Acute Myelogenous Leukemia or Myelodysplastic Syndromes PHASE1 This study is being performed to assess the safety, tolerability, and preli...
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UCLA Medical Center
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Ulixertinib (BVD-523) and Hydroxychloroquine in Patients W Advanced MAPK-Mutated Gastrointestinal Adenocarcinomas PHASE1 Open-label dose escalation of Ulixertinib combined with fixed dose of hydro...
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Huntsman Cancer Institute
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Ulixertinib in Treating Patients With Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With MAPK Pathway Mutations (A Pediatric MATCH Treatment Trial) PHASE2 This phase II Pediatric MATCH trial studies how well ulixertinib works in t...
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Location
Children's Hospital of Alabama
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Targeted Therapy Directed by Genetic Testing in Treating Patients With Advanced Refractory Solid Tumors, Lymphomas, or Multiple Myeloma (The MATCH Screening Trial) PHASE2 This phase II MATCH screening and multi-sub-trial studies how well treatmen...
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Location
University of Alabama at Birmingham Cancer Center
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Phase I Dose-Escalation, Safety, Pharmacokinetic and Pharmacodynamic Study of BVD-523 in Patients With Advanced Malignancies PHASE1 This open-label, multi-center Phase 1/2 study will assess the safety, pharm...
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UCLA Med-Hematology & Oncology
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Study of Ulixertinib for Patients With Advanced Malignancies Harboring MEK or Atypical BRAF Alterations PHASE2 This BVD-523-ABC study builds on the safety and clinical activity experienc...
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Expanded Access to Ulixertinib (BVD-523) in Patients With Advanced MAPK Pathway-Altered Malignancies N/A The objective of this expanded access program is to provide ulixertinib (BV...
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Infirmary Cancer Care
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A Study of Ruxolitinib in Combination With Ulixertinib in People With Myelofibrosis PHASE1 The researchers are doing this study to find out whether the combination of...
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Massachusetts General Hospital (Data Collection Only)
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Window-of-Opportunity Trial of Ulixertinib for MAPK-Activated Gliomas EARLY_PHASE1 To learn if the study drug, ulixertinib, can cross over the blood-brain bar...
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M D Anderson Cancer Center
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