Found 10 matching trials
Long-term Extension Study of Setrusumab in Adults With Type I, III, or IV Osteogenesis Imperfecta
PHASE2The primary objective of the study is to evaluate bone mineral density (BMD...
Location
New Mexico Clinical Research & Osteoporosis Center
Setrusumab vs Placebo for Osteogenesis Imperfecta
PHASE2The primary objectives of the study are to identify a setrusumab dosing str...
Status
Active Not Recruiting
Location
Arkansas Children's Hospital
An Exploratory Study of BPS804 Treatment in Adult Patients With Type I, III or IV Osteogenesis Imperfecta
PHASE2The purpose of this study is to investigate the effect of BPS804 on strengt...
Location
Mereo Investigator Site
Dose Escalation Study to Evaluate the Safety and Tolerability of Multiple Infusions of BPS804 in Adults With Hypophosphatasia (HPP)
PHASE2The purpose of the study is to determine tolerability, PK/PD and preliminar...
Location
Mereo BioPharma 3 Ltd Investigative Site
Setrusumab vs Bisphosphonates in Pediatric Subjects With Osteogenesis Imperfecta
PHASE3The primary objective of the study is to evaluate the effect of setrusumab ...
Status
Active Not Recruiting
Location
Phoenix Children's Hospital
A Study in Adult Patients With Type I, III or IV Osteogenesis Imperfecta Treated With BPS804
PHASE2The purpose of this study is to select a suitable dose of BPS804 by measuri...
Location
Mereo Investigator Site
Study of Safety and Tolerability of BPS804 in Patients With Late-stage Chronic Kidney Disease
PHASE2The purpose of the study is to evaluate the safety, tolerability, and PK fo...
Location
Multiple Locations
Safety and Efficacy of Multiple Dosing Regimens of BPS804 in Post Menopausal Women With Low Bone Mineral Density
PHASE2This study is designed to provide information on the safety, tolerability, ...
Location
Novartis Investigative Site
Safety, Pharmacokinetics and Pharmacodynamics of BPS804 in Osteogenesis Imperfecta
PHASE2This is a randomized, open label intra-patient dose escalation study to eva...
Location
Novartis Investigative Site
Setrusumab in Pediatric Japanese Subjects With Osteogenesis Imperfecta
PHASE3The primary objective of the study is to evaluate the effect of setrusumab ...
Status
Active Not Recruiting
Location
Osaka Metropolitan University Hospital