Found 14 matching trials
A Randomized Study of BPN14770 in Male Adolescents (Aged 9 to < 18 Years) With Fragile X Syndrome
PHASE2This is a 2-part study, with each part having a unique set of objectives fo...
Location
Amnova Clinical Research
A Phase 1, Open-Label, PET Study of T2310 & BPN14770
PHASE1This is a sponsor initiated, single site, first-in-human study of an invest...
Location
Weill Cornell Medicine
Tetra PICASSO AD Trial: Study to Evaluate Effects of BPN14770 in Early Alzheimer's Subjects
PHASE2A Randomized, Double-blind, Placebo Controlled, 3-Arm Parallel Design Study...
Location
Generations at Agritopia/CCT Research
A 2-Period Crossover Study of BPN14770 in Adults Males With Fragile X Syndrome
PHASE2This is a single-center, randomized, double-blind, 2-period crossover study...
Location
Rush University Medical Center
An Open-Label Extension Study of BPN14770 in Subjects With Fragile X Syndrome
PHASE3This is a 4-year, open-label extension (OLE) study for subjects completing ...
Status
Active Not Recruiting
Location
Amnova Clinical Research
Study of Zatolmilast (BPN14770) in Participants With PPP2R5D Neurodevelopmental Disorder (Jordan's Syndrome [JS])
PHASE2The primary objective of this study is to assess the efficacy, safety, and ...
Status
Active Not Recruiting
Location
Rush University Medical Center
A Study of BPN14770 in Male Adults (Aged 18 to 45) With Fragile X Syndrome
PHASE3A Randomized, Double-blind, Placebo-controlled, Parallel Group Study of BPN...
Location
Amnova Clinical Research
Title: Evaluation of a Novel PET Radioligand for Phosphodiesterase-4D (PDE4D)
PHASE1Background:
The brain enzyme phosphodiesterase-4D (PDE4D) may affect think...
Location
National Institutes of Health Clinical Center
A Multiple Ascending Dose Study of BPN14770 in Healthy Young and Elderly Male or Female Subjects
PHASE1This is a randomized, double-blind (Investigator and subject-blinded) place...
Phase 1 Study of BPN14770 in Participants With Hepatic Impairment and Healthy Controls
PHASE1The primary purpose of this study is to assess the pharmacokinetics (PK) of...
Location
Division of Clinical Pharmacology, University of Miami