Found 12 matching trials
Trial of Erlotinib and BKM120 in Patients With Advanced Non Small Cell Lung Cancer Previously Sensitive to Erlotinib
PHASE2Preclinical data in lung cancer cell lines showed that EGFR mutation can po...
Location
Florida Cancer Specialists South
Dose Finding Study of BKM 120 in Combination With LH-RH Agonists and Bicalutamide in Men With Non Castrate Metastatic Prostate Cancer
PHASE1To determine the maximum-tolerated dose (MTD) of BKM120 when administered o...
Location
Institut Paoli Calmettes
Phase II, Open Label, Non-randomized, Trial of BKM120 for Metastatic or Locally Advanced Cervical Cancer
PHASE2This is a single arm open label phase II trial to evaluate the oral daily u...
Location
Novartis Investigative Site
A Multicenter Phase II Pilot Open Label
PHASE2In France, 7-8 000 new thyroid cancer cases are diagnosed each year. Althou...
Location
Hospices Civils de Lyon
PhIb BKM120 or BEZ235+Endocrine Treatment in Post-Menopausal Patients With Hormone Receptor + Metastatic Breast Cancer
PHASE1This is an open-label phase Ib multi-institution trial that evaluates the s...
Location
University of Alabama
Study of BKM120 or BYL719 and Capecitabine in Patients With Metastatic Breast Cancer
PHASE1This phase I study has been designed to establish the safety, tolerability ...
Location
Lineberger Comprehensive Cancer Center
Combination of BKM120 and Bevacizumab in Refractory Solid Tumors and Relapsed/Refractory Glioblastoma Multiforme
PHASE1In this phase I/II study,investigators are evaluating the feasibility and e...
Location
Yale School of Medicine
Phase Ib, Dose Escalation Study of Oral LDE225 in Combination With BKM120 in Patients With Advanced Solid Tumors
PHASE1The purpose of this study is to determine the maximum dose of LDE225 and BK...
Location
Cedars Sinai Medical Center SC
Cisplatin, Etoposide and PI3K Inhibitor BKM120 in Treating Patients With Advanced Solid Tumors or Small Cell Lung Cancer
PHASE1This phase I trial studies the side effects and the best dose of PI3K inhib...
Location
University of California at Davis Cancer Center
BKM120 and Fulvestrant for Treating Postmenopausal Patients With Estrogen Receptor-Positive Stage IV Breast Cancer
PHASE1This phase I trial will determine the Maximum Tolerated Dose (MTD) of BKM12...
Location
Washington University School of Medicine