Found 242 matching trials
Neoadjuvant Radiotherapy Plus Targeted Therapy and Immunotherapy vs. Targeted Therapy Plus Immunotherapy in Resectable HNSCC PHASE2 This study compares the efficacy of neoadjuvant low-dose radiotherapy plus ...
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Multiple Locations
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Adjuvant Afatinib in Stage I-III NSCLC With EGFR Mutation PHASE2 This research study is a Phase II clinical trial, which tests the safety an...
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Stanford University
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High Throughput Drug Sensitivity Assay and Genomics- Guided Treatment of Patients With Relapsed or Refractory Acute Leukemia NA This pilot clinical trial studies the feasibility of choosing treatment bas...
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Fred Hutch/University of Washington Cancer Consortium
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The ATTAIN Study: A Therapeutic Trial of Afatinib In the Neoadjuvant Setting PHASE2 The goal of this clinical research study is to learn if it is tolerable for...
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University of Texas MD Anderson Cancer Center
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LUX-Breast 1: BIBW 2992 (Afatinib) in HER2-positive Metastatic Breast Cancer Patients After One Prior Herceptin Treatment PHASE3 To investigate the efficacy and safety of BIBW 2992 in combination with vin...
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Achieve Clinical Research, LLC
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A Biomarker-implemented Clinical Study Evaluating Mutations in MET and TP53 in a Population of Treatment-refractory Squamous Cell Carcinoma PHASE2 Afatinib is approved therapy for SCC of the lung after progression with sta...
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National University Hospital
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Phase 2 Trial of Afatinib Plus Prednisone for Advanced Squamous NSCLC PHASE2 To determine the efficacy of combined afatinib and prednisone in previously...
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Active Not Recruiting
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UT Southwestern Medical Center
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A Phase II Trial of Weekly Alternating Sequential Administration of BIBF 1120 and BIBW 2992 in Patients With Advanced Colorectal Cancer PHASE2 The primary objective of this trial is to explore the overall objective bes...
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1239.2.3305A clinique Saint Jean
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Influence of Mild and Moderate Hepatic Impairment on the Pharmacokinetics, Safety and Tolerability of Various Doses of Afatinib PHASE1 Up to 38 subjects entered with the aim of entering 8 subjects with mild liv...
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1200.86.1 Boehringer Ingelheim Investigational Site
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LUX-Head&Neck 3: Afatinib (BIBW2992) Versus Methotrexate for the Treatment of Recurrent and/or Metastatic Head and Neck Squamous Cell Cancer After Platinum Based Chemotherapy PHASE3 This randomized, open-label, phase III study will be performed in patients ...
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Beijing Chao-Yang Hospital
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