Found 73 matching trials
Treatment of CD79B Mutant Relapsed/Refractory Diffuse Large B-Cell Lymphoma With Bruton Tyrosine Kinase Inhibitor Zanubrutinib PHASE2 The goal of this clinical trial was to evaluate whether zanubrutinib can ef...
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Anhui Provincial Cancer Hospital Aka West Branch of Anhui Province Hospital
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Zanubrutinib (BGB-3111) in Participants With Previously Treated B-Cell Lymphoma Intolerant of Prior Bruton Tyrosine Kinase Inhibitor (BTKi) Treatment PHASE2 The primary objective of this study is to evaluate the safety of zanubrutin...
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Rocky Mountain Cancer Centers (Williams) Usor
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Study of Zanubrutinib (BGB-3111) in Participants With Marginal Zone Lymphoma PHASE2 This is a single arm study to evaluate the efficacy, safety and tolerabilit...
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Clinical Research Alliance, Inc
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Patient-Derived Xenografts in Personalizing Treatment for Patients With Relapsed/Refractory Mantle Cell Lymphoma EARLY_PHASE1 This early phase I pilot trial studies how well patient-derived xenografts ...
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M D Anderson Cancer Center
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Interaction Study of Zanubrutinib With Moderate and Strong CYP3A Inhibitors in Participants With B-Cell Malignancies PHASE1 The primary objective of this study was to assess the steady-state zanubrut...
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Concord Repatriation General Hospital
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A Two-Part Phase 1 Study to Investigate the Safety and Tolerability of Supratherapeutic Dose of Zanubrutinib and Effect of Zanubrutinib on Cardiac Repolarization in Healthy Subjects PHASE1 A Two-Part Phase 1 Study to Investigate A) Safety and Tolerability of Supra...
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Frontage Clinical Services, Inc.
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A Pharmacokinetic Study to Assess Drug-drug Interaction Between Zanubrutinib and a Cocktail of Substrates in Healthy Subjects PHASE1 This study is designed to evaluate the safety and pharmacokinetic interacti...
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Covance Clinical Research Unit
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Zanubrutinib in Combination With R-PolaCHP (ZaR-PolaCHP) for Newly Diagnosed Diffuse Large B-Cell Lymphoma PHASE1 This phase Ib trial seeks to find out the best dose and possible side effec...
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Active Not Recruiting
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A Study of Nemtabrutinib (MK-1026) in Participants With Relapsed or Refractory Hematologic Malignancies (ARQ 531-101/MK-1026-001) PHASE1 This study aims to evaluate the safety, tolerability, pharmacodynamic, and ...
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Active Not Recruiting
Location
Mayo Clinic Hospital ( Site 0140)
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Study of BTK Inhibitor Zanubrutinib in Participants With Relapsed/Refractory Non-GCB Type Diffuse Large B Cell Lymphoma PHASE2 Screening (up to 28 days); daily treatment until disease progression, unacc...
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Beijing Cancer Hospital
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