Found 15 matching trials
Exploring the Immune Response to SARS-CoV-2 modRNA Vaccines in Patients With Secondary Progressive Multiple Sclerosis (AMA-VACC) PHASE4 The purpose of this study was to understand whether participants could moun...
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Novartis Investigative Site
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Exploring the Efficacy and Safety of Siponimod in Patients With Secondary Progressive Multiple Sclerosis (EXPAND) PHASE3 Evaluate the safety and efficacy of Siponimod (BAF312) versus placebo in a ...
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Novartis Investigative Site
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A Single-dose, Open-label, Parallel-group Study to Assess the Pharmacokinetics of BAF312 in Subjects With Renal Impairment Compared to Subjects With Normal Renal Function PHASE1 to quantify the effect of different degrees of renal impairment on the phar...
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Novartis Investigative Site
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Single Dose Study to Assess the Safety, Tolerability, Concentration in Body and Effect of BAF312 PHASE1 The purpose of this study is to assess the safety, tolerability, and effect...
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Safety and Tolerability of Conversion From Oral, Injectable, or Infusion Disease Modifying Therapies to Dose-titrated Oral Siponimod (Mayzent) in Advancing RMS Patients PHASE3 To assess safety and tolerability of patients converting from approved Rela...
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Novartis Investigative Site
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Repurposing Siponimod for Alzheimer's Disease PHASE2 Collaboration with multiple sclerosis (MS) specialty colleagues led us to f...
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St. Joseph's Hospital and Medical Center
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Efficacy and Tolerability of BAF312 in Patients With Polymyositis and Dermatomyositis PHASE2 This study determined the efficacy, safety, tolerability and the PK profile...
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Novartis Investigative Site
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Safety and Efficacy of BAF312 in Dermatomyositis PHASE2 This study investigated the dose response relationship for the efficacy and...
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Novartis Investigative Site
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Safety, Tolerability, Efficacy and Optimal Dose Finding Study of BAF312 in Patients With Relapsing-remitting Multiple Sclerosis PHASE2 The purpose of this study was to determine the dose-response curve for the ...
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Novartis Investigative Site
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Pharmacokinetics of BAF312 in Patients With Hepatic Impairment PHASE1 This study will investigate the pharmacokinetics of BAF312 in patients with...
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Novartis Investigative Site
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