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A Trial of Oral 5-azacitidine in Combination With Romidepsin in Advanced Solid Tumors, With an Expansion Cohort in Virally Mediated Cancers and Liposarcoma PHASE1 The purpose of this study is to determine whether 5-azacitidine in combinat...
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Sidney Kimmel Cancer Center @ Johns Hopkins
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Venetoclax to Augment Epigenetic Modification and Chemotherapy PHASE1 The investigator is testing the addition of venetoclax to 5-azacitidine and...
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Children's Wisconsin
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A Phase 1b Study of Lonitoclax + Azacitidine in Acute Myeloid Leukemia Patients PHASE1 This is a clinical study aiming to evaluate the safety, pharmacokinetics, p...
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Multiple Locations
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Study of a Novel BET Inhibitor FT-1101 in Patients With Relapsed or Refractory Hematologic Malignancies PHASE1 This is an open-label, multicenter, dose-escalation Phase 1/1b study in pat...
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Magrolimab Monotherapy or Magrolimab in Combination With Azacitidine in Participants With Hematological Malignancies PHASE1 The primary objectives of this study are:
* To confirm the safety and tole...
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City of Hope National Medical Center
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A Study to Investigate APL-4098 Alone and in Combination in Adults With AML or MDS PHASE1 This is an open-label, Phase 1 study to determine the safety, tolerability,...
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A Study of Decitabine in Combination With Escalating Doses of Rapamycin in Patients With Relapsed or Refractory Acute Myeloid Leukemia PHASE1 The purpose of this study is to determine the safety and feasibility of the...
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University of Rochester
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Epigenetic Priming Using Azacitidine With Neoadjuvant Chemotherapy for Resectable Esophageal Cancer PHASE1 The purpose of this study is to see whether giving azacitidine before each ...
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Weill Cornell Medical College
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A Study of ARGX-110 in Combination With Azacytidine in Participants With Newly Diagnosed Acute Myeloid Leukemia (AML) or High Risk Myelodysplatic Syndrome (MDS) PHASE1 The purpose of this study is to determine the maximum tolerated dose (MTD) ...
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Multiple Locations
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Birinapant With 5-azacitidine in MDS Subjects Who Are Naïve, Have Relapsed or Are Refractory to 5-azacitidine Therapy PHASE1 This is a dose escalation followed by dose expansion study of TL32711 in co...
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Palo Verde Hematology Oncology
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