Found 11 matching trials
Phase 2 Study of Pracinostat With Azacitidine in Patients With Previously Untreated Myelodysplastic Syndrome PHASE2 The purpose of this randomized, double-blind, placebo-controlled study is t...
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Southern Cancer Center
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A Study of JNJ-90189892 for Relapsed or Refractory Acute Myeloid Leukemia or Myelodysplastic Neoplasms PHASE1 The purpose of Part 1 (Dose Escalation) of the study is to assess the effec...
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Sirolimus and Azacitidine in Treating Patients With High Risk Myelodysplastic Syndrome or Acute Myeloid Leukemia That is Recurrent or Not Eligible for Intensive Chemotherapy PHASE2 This phase II trial studies how well sirolimus and azacitidine works in tre...
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Jefferson Health NJ Division (Kennedy Hospital)
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Phase 2 Study Adding Pracinostat to a Hypomethylating Agent (HMA) in Patients With MDS Who Failed to Respond to Single Agent HMA PHASE2 The purpose of this open label study is to determine whether combining prac...
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Southern Cancer Center
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Study of Azacitidine in Combination With Pembrolizumab in R/R AML Patients and in Newly Diagnosed Older Patients PHASE2 This is a multicenter, nonrandomized, open-label phase 2 study (with a safe...
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Johns Hopkins Oncology Center
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Window Trial 5-aza in HNSCC, T-tare PHASE1 The purpose of this study is to assess the activity of 5-azacitidine in pat...
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Smilow Cancer Center at Yale New Haven Hospital
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BLAST MRD AML-2: BLockade of PD-1 Added to Standard Therapy to Target Measurable Residual Disease in Acute Myeloid Leukemia 2- A Randomized Phase 2 Study of Anti-PD-1 Pembrolizumab in Combination With Azacitidine and Venetoclax as Frontline Therapy in Unfit Patients With Acute Myeloid Leukemia PHASE2 This phase II trial studies how well azacitidine and venetoclax with or wit...
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Active Not Recruiting
Location
Smilow Cancer Hospital Care Center at Greenwich
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Safety and Efficacy Study of Pracinostat With Azacitadine in Elderly Patients With Newly Diagnosed Acute Myeloid Leukemia (AML) PHASE2 The purpose of this study is to determine the safety and effectiveness of p...
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City of Hope Comprehensive Cancer Ctr
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Vidaza and Valproic Acid Post Allogeneic Transplant for High Risk AML and MDS PHASE2 Phase II trial combining azacitidine with valproic acid as maintenance ther...
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Loyola University Cardinal Bernardin Cancer Center
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The Efficacy of Triple Regimen in Newly Diagnosed AML Patients With FLT3 Mutation PHASE1 The FMS tyrosine kinase 3 (FLT3) gene mutation occurs in 30% of newly diagn...
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Blood Diseases Hospital
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