Found 26 matching trials
Phase Ib Study of Avutometinib, Defactinib, and Everolimus in RAS Pathway Mutant Endometrial Cancer
PHASE1To find the recommended dose of the combination of avutometinib, defactinib...
Location
MD Anderson Cancer Center
Defactinib, Avutometinib and Nivolumab for the Treatment of Anti-PD1 Refractory LKB1-Mutant Advanced Non-Small Cell Lung Cancer
PHASE2This phase II trial tests how well defactinib and avutometinib in combinati...
Location
Emory University Hospital Midtown
Stereotactic Body Radiotherapy Plus FAK and RAF/MEK Inhibition in Advanced Pancreatic Adenocarcinoma
PHASE2Advanced pancreatic cancer patients receiving treatment of adaptive stereot...
Location
Washington University School of Medicine
A Study of Avutometinib + Defactinib in Recurrent Low-Grade Serous Ovarian Cancer in Japanese Patients
PHASE2This study will confirm the safety and efficacy of avutometinib in combinat...
Status
Active Not Recruiting
Location
Aichi Cancer Center Hospital
VS-6766+Abema+Fulv in Met HR+/HER- BC
PHASE1This research is being done to evaluate the safety and effectiveness of a d...
Location
Massachusetts General Hospital Cancer Center
Study of Avutometinib (VS-6766) + Adagrasib in KRAS G12C NSCLC Patients
PHASE1This study will assess the safety and efficacy of avutometinib (VS-6766) in...
Location
UCSF Thoracic Oncology
A Study of Avutometinib (VS-6766) + Defactinib in Recurrent KRAS G12V, Other KRAS and BRAF Non-Small Cell Lung Cancer
PHASE2This study will assess the safety and efficacy of avutometinib (VS-6766) mo...
5G-RUBY: Avutometinib and Defactinib in Malignant Brain Tumours
PHASE1The purpose of this clinical trial is to evaluate the safety and tolerabili...
Location
Cambridge University Hospitals
A Study of Avutometinib (VS-6766) and Defactinib in People With Mesonephric Gynecologic Cancer
PHASE2This study will test if Avutometinib (VS-6766) in combination with Defactin...
Location
Memorial Sloan Kettering Basking Ridge (Limited Protocol Activities)
Defactinib and Avutometinib, With or Without Encorafenib, for the Treatment of Patients With Brain Metastases From Cutaneous Melanoma
PHASE1The goal of this interventional clinical trial is to provide proof-of-princ...
Location
University of Iowa