Found 16 matching trials
Sanaria PfSPZ Challenge With Pyrimethamine or Chloroquine Chemoprophylaxis Vaccination (PfSPZ-CVac Approach): A Randomized Double Blind Placebo Controlled Phase I/II Trial to Determine Safety and Protective Efficacy Against Natural Plasmodium Falcipa... PHASE1 Background:
Malaria remains a major global health problem. Malaria is spre...
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Malaria Vaccine Center STTB/MRTC
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Assess Safety, Tolerability, Pharmacokinetic and Pharmacodynamic Profile of Ruxolitinib With Artemether-lumefantrine PHASE1 Phase 1, single -center study in 2 parts. The study designs for each part a...
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Nucleus Network Brisbane
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A Trial to Compare the Efficacy, Safety and Tolerability of Combinations of 3 Anti-malarial Drugs Against Combinations of 2 Anti-malarial Drugs (Asia) PHASE3 A partially blinded randomised controlled non-inferiority trial comparing t...
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Ramu Upazilla Health Complex
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Trial of Artemether-Lumefantrine Alone and in Combination With Ivermectin to Reduce Post-Treatment Malaria Transmission PHASE1 The purpose of this study is to determine the safety and impact of ivermect...
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Centre National de Recherche et de Formation sur le Paludisme
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Safety and Protective Efficacy of Genetically Attenuated PfSPZ-GA1 Vaccine in Healthy Dutch Volunteers PHASE1 This is a first-in-human, randomized clinical trial of PfSPZ-GA1 Vaccine (g...
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Leiden University Medical Center, Albinusdreef 2
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A Trial to Compare the Efficacy, Safety and Tolerability of Combinations of 3 Anti-malarial Drugs Against Combina-tions of 2 Anti-malarial Drugs. PHASE3 A partially blinded randomised controlled non-inferiority trial comparing t...
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Institut des Sciences et Techniques (INSTech)
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"Prolonging the Therapeutic Life Span of Artemisinin-based Combination Therapies (ACT) in Bagamoyo District, Tanzania" PHASE4 This clinical trial evaluates the advantage of prolonging the therapeutic l...
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Fukayosi Dispensary
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A Study to Assess the Safety and Efficacy of 5-aminolevulinic Acid Hydrochloride (5-ALA HCl) and Sodium Ferrous Citrate (SFC) Added on Artemisinin-based Combination Therapy (ACT) in Adult Patients With Uncomplicated Malaria PHASE2 This is a pilot, double-blind, randomized, parallel-group, placebo-control,...
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Multiple Locations
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Triple Artemisinin-based Combination Therapy for Delaying Drug Resistance Development - a Randomized Clinical Trial PHASE2 Background: Artemisinin resistance has emerged in parts of Southeast Asia, ...
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Pyronaridine Artesunate (3:1) Versus Coartem® in P Falciparum Malaria Patients PHASE3 The primary objective of this phase III study is to compare the efficacy an...
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Ecole de Santé Publique, Faculté de Médecine, Université de Kinshasa
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