Found 16 matching trials
Effect of Apelin on Insulin Sensitivity in Type 2 Diabetic Volunteers
PHASE1Preclinical studies have demonstrated in mouse models that (PYR1)-apelin-13...
Location
University Hospitals of Toulouse (Rangueil)
Cardiovascular Effects of Apelin In Healthy Volunteers
EARLY_PHASE1Apelin is an endogenous peptide with physiological actions in the cardiovas...
Location
Clinical Research Facility University of Edinburgh
Apelin as a Potential Treatment for Chronic Kidney Disease
NAChronic kidney disease (CKD) affects 8-16% of the world's population, and i...
Location
Clinical Research Centre, Western General Hospital
Investigating Systemic and Local Vascular Responses to Apelin in the Context of Renin-angiotensin Upregulation
NAThe apelin-APJ system is a relatively new discovery. It has generated inter...
Location
Clincial Research Facility, Royal Infirmary of Edinburgh, 51 Little France Cresc
Haemodynamic Effects of Apelin Agonists and Antagonists in Man in COPD With Raised Pulmonary Artery Pressures
NAThe investigators are interested in studying how Pulmonary Hypertension occ...
Location
Vascular Research Unit, Clinical Pharmacology Unit, ACCI, Level 3, Addenbrooke's Hospital, Hills Road
Effects of Intravenous [Pyr1]Apelin-13 on Healthy Volunteers With Artificially Induced SIAD
NAHyponatremia is a common electrolyte imbalance which often results from hor...
Location
University Hospital Basel
Effect of Apelin on Insulin Sensitivity: Proof of Concept in Healthy Volunteers
PHASE1The (PYR1)-apelin-13 is an endogenous peptide discovered relatively recentl...
Location
University Hospital of Toulouse
Interaction of Apelin and Angiotensin in the Human Forearm Circulation
NAThe apelin-APJ system is a relatively new discovery. It has generated inter...
Location
Clincial Research Facility, Royal Infirmary of Edinburgh, 51 Little France Cresc
A Study of CLR325 in Chronic Stable Heart Failure Patients.
PHASE2The purpose of this study was to determine the safety and tolerability of C...
Location
Novartis Investigative Site
The Study of Apelin-APJ System on Pulmonary Hypertension Patients and Healthy Subjects
PHASE1The purpose of this study is to
* Determine blood peptide levels and inves...
Location
Hammersmith Hospital, Imperial College London