Found 13 matching trials
Bispecific CD19/CD22 CAR-T for Treatment of Children and Young Adults With r/r B-ALL PHASE1 The purpose of this study is to evaluate the safety and efficiency of autol...
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Active Not Recruiting
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Federal Research Institute of Pediatric Hematology, Oncology and Immunology
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Anti-CD19/CD22 Bispecific Chimeric Antigen Receptor(CAR)-T Cell Therapy for Measurable Residual Disease(MRD) Positive ALL PHASE1 To evaluate the safety and efficacy of CD19/CD22 Bispecific chimeric antige...
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Shanghai General Hospital
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Anti-CD22 CAR-T Cell Therapy Targeting B Cell Malignancies PHASE1 The study will evaluate safety and efficacy of the CD22-targeted chimeric a...
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Pilot Study of Autologous Anti-CD22 Chimeric Antigen Receptor Redirected T Cells In Patients With Chemotherapy Resistant Or Refractory Acute Lymphoblastic Leukemia PHASE1 This is a single center, single arm, open-label pilot study to determine th...
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Abramson Cancer Center of the University of Pennsylvania
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Treatment of Relapsed and/or Chemotherapy Refractory B-cell Malignancy by Tandem CAR T Cells Targeting CD19 and CD22 PHASE1 RATIONALE: Placing a tumor antigen chimeric receptor that has been created ...
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Biotherapeutic Department and Pediatrics Department of Chinese PLA General Hospital
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Anti-CD19/CD22 Bispecific CAR-T Cell Therapy for CD19-positive ALL PHASE1 The goal of this clinical trial is to study the feasibility and efficacy of...
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Henan Province of TCM
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CART22 Alone or in Combination With huCART19 for ALL PHASE1 This is a single center, open-label, phase 1 study to determine the safety ...
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Location
University of Pennsylvania
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Anti-CD22 Chimeric Antigen Receptor (CAR)-Modified T Cell Therapy for Relapsed Refractory B-cell Malignancies PHASE1 This is a single-center, open-label, single-arm study to evaluate the safet...
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Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
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Anti-CD22 CAR-T Therapy for CD19-refractory or Resistant Lymphoma Patients PHASE1 The goal of this clinical trial is to study the feasibility and efficacy of...
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Department of Oncology, Xinqiao Hospital
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CD19/CD22 Chimeric Antigen Receptor (CAR) T Cells in Children and Young Adults With Recurrent or Refractory CD19/CD22-expressing B Cell Malignancies PHASE1 Background:
B-cell leukemias and lymphomas are cancers that are often diff...
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National Institutes of Health Clinical Center
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