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The Drug Rediscovery Protocol (DRUP Trial) PHASE2 This is a prospective, non-randomized clinical trial that aims to describe ...
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Noordwest ziekenhuisgroep Alkmaar (NWZ)
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A Phase II, Open Label, Multiple Arm Study of AUY922, BYL719, INC280, LDK378 and MEK162 in Chinese Patients With Advanced Non-small Cell Lung Cancer PHASE2 The purpose of this study was to evaluate the anti-tumor activity of single...
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Novartis Investigative Site
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Alpelisib and Enzalutamide in Treating Patients With Androgen Receptor and PTEN Positive Metastatic Breast Cancer PHASE1 This phase I trial studies the side effects and best dose of alpelisib when...
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M D Anderson Cancer Center
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Study Assessing the Efficacy and Safety of Alpelisib Plus Fulvestrant or Letrozole, Based on Prior Endocrine Therapy, in Patients With PIK3CA Mutant, HR+, HER2- Advanced Breast Cancer Who Have Progressed on or After Prior Treatments PHASE2 This was a Phase II, multicenter, open-label, three-cohort, non-comparative...
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Banner MD Anderson Cancer Center
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Study of LEE011, BYL719 and Letrozole in Advanced ER+ Breast Cancer PHASE1 The purpose of this trial is to inform the future clinical development of t...
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Active Not Recruiting
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Univ of California at San Diego Moores Cancer Ctr
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A Phase Ib/II Study of the Combination of BYL719 Plus AMG 479 in Adult Patients With Selected Solid Tumors PHASE1 This was a multi-center, open-label, phase Ib/II study. The aim of the phas...
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Novartis Investigative Site
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Olaparib and Alpelisib for Treatment of Metastatic Breast Cancer, A ComboMATCH Treatment Trial PHASE2 This phase II ComboMATCH treatment trial studies the effect of adding a dru...
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Multiple Locations
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SMMART Adaptive Clinical Treatment (ACT) Trial EARLY_PHASE1 SMMART-ACT is a feasibility pilot study to determine if testing samples fro...
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Multiple Locations
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EPIK-P4: A Phase II Single-arm Study to Assess the Efficacy, Safety and Pharmacokinetics of Alpelisib (BYL719) in Pediatric and Adult Patients With PIK3CA-related Overgrowth Spectrum (PROS) PHASE2 This study is designed to demonstrate the efficacy and assess safety and to...
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Washington University
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Human Models of Selective Insulin Resistance: Alpelisib, Part I PHASE1 The goal of this clinical trial is to understand how the blood sugar-loweri...
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Columbia University Irving Medical Center
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