Found 66 matching trials
Aurora A Kinase Inhibitor MLN8237 in Treating Patients With Unresectable Stage III-IV Melanoma PHASE2 RATIONALE: Aurora A kinase inhibitor MLN8237 may stop the growth of tumor c...
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Vanderbilt-Ingram Cancer Center
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Alisertib With or Without Fulvestrant in Treating Patients With Locally Advanced or Metastatic, Endocrine-Resistant Breast Cancer PHASE2 This phase II trial studies how well alisertib with or without fulvestrant ...
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Georgetown University Medical Center
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Targeting Aurora A Kinase to Overcome Treatment Resistance in Advanced HR+/HER2+ Breast Cancer PHASE2 The goal of this clinical trial is to learn if alisertib in addition to usu...
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University of Wisconsin Carbone Cancer Center
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Phase II Trial of Alisertib (MLN8237) in Salvage Malignant Mesothelioma PHASE2 Objectives:
Objectives
The primary objective of this study is to:
To ass...
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University of Texas MD Anderson Cancer Center
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Study to Compare Alisertib With Paclitaxel vs. Paclitaxel Alone in Metastatic or Locally Recurrent Breast Cancer PHASE2 The goal of this clinical research study is to learn if the study drug, ali...
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Phase II Trial of Alisertib With Induction Chemotherapy in High-risk AML PHASE2 This research study is studying a targeted therapy (a form of treatment tha...
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Massachusetts General Hospital
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Study of Alisertib (MLN8237) in Adults With Aggressive Non-Hodgkin's Lymphoma PHASE2 The purpose of this study is to evaluate the anti-tumor activity of alisert...
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Hematology Oncology Associates, Virtua Memorial Hospital Burlington County
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Alisertib in Combination With Vorinostat in Treating Patients With Relapsed or Recurrent Hodgkin Lymphoma, B-Cell Non-Hodgkin Lymphoma, or Peripheral T-Cell Lymphoma PHASE1 This phase I trial studies the side effects and the best dose of alisertib ...
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City of Hope Comprehensive Cancer Center
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Study of MLN8237 in Combination With Irinotecan and Temozolomide PHASE1 The goal of the first part of this clinical trial (Phase I portion) is to s...
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Children's Hospital Los Angeles
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MLN8237 to Treat Children With Relapsed/Refractory Solid Tumors PHASE1 RATIONALE: MLN8237 may stop the growth of cancer cells by blocking some of ...
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Multiple Locations
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