Found 533 matching trials
Inhaled Interleukin-2 in Treating Patients With Metastatic or Unresectable Cancer PHASE1 RATIONALE: Interleukin-2 may stimulate a person's white blood cells to kill...
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USC/Norris Comprehensive Cancer Center
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Adaptive Study of IL-2 Dose Frequency on Regulatory T Cells in Type 1 Diabetes PHASE1 Type 1 diabetes (T1D) is the most common severe autoimmune disease worldwid...
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Wellcome Trust Clinical Research Facility, Addenbrookes Hospital
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Monoclonal Antibody Therapy and Interleukin-2 in Treating Patients With Metastatic Melanoma PHASE1 RATIONALE: Biological therapies, such as MDX-010, work in different ways to...
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Warren Grant Magnuson Clinical Center - NCI Clinical Studies Support
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T-regulatory Cells in ALS PHASE2 This study is a randomized, placebo-controlled, phase 2a trial to study the...
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Active Not Recruiting
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Massachusetts General Hospital Neurological Clinical Research Institute
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Laboratory-Treated Autologous Lymphocytes, Aldesleukin, and GM-CSF in Treating Patients With Recurrent, Refractory, or Metastatic Non-Small Cell Lung Cancer PHASE1 RATIONALE: Giving autologous lymphocytes that have been treated in the labo...
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Roger Williams Medical Center
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To Evaluate the Safety and Efficacy of ADP-TILIL7 in Patients With Locally Advanced or Metastatic Melanoma PHASE1 The primary objective of this Phase 1 clinical trial is to evaluate the fea...
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Department of Oncology
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Pembrolizumab, Standard Chemotherapy, Tumor Infiltrating Lymphocytes, and High- or Low-Dose Aldesleukin in Treating Patients With Metastatic Melanoma PHASE2 This randomized phase II trial studies how well giving pembrolizumab with s...
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M D Anderson Cancer Center
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A Study of Gene Edited Autologous Neoantigen Targeted TCR T Cells With or Without Anti-PD-1 in Patients With Solid Tumors PHASE1 This is a first in human, single arm, open label, Phase 1a/1b study to dete...
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Combination Chemotherapy Followed by Peripheral Stem Cell Transplantation and Interleukin-2 in Treating Patients With Acute Leukemia PHASE2 RATIONALE: Drugs used in chemotherapy use different ways to stop cancer cel...
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Herbert Irving Comprehensive Cancer Center at Columbia University
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TIL Therapy for Metastatic Ovarian Cancer PHASE1 Adoptive T cell therapy with tumor infiltrating lymphocytes (TIL) has achie...
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Center for Cancer Immune Therapy Dept. of Hematology/oncology
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