Found 9 matching trials
Phase I Trial of Afatinib (BIBW 2992) and Dasatinib in Non-small Cell Lung Cancer (NSCLC) PHASE1 The purpose of this study is to:
* Find out if the study drugs Afatinib an...
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H. Lee Moffitt Cancer Center and Research Institute
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A Study of Intermittent, High-dose Afatinib to Determine the Maximal Tolerated Dose and Assess Activity of This Dose Against Non-small Cell Lung Cancer With T790M Mutations PHASE1 This trial is divided into Part A and Part B. The primary objective of Part...
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Boehringer Ingelheim Investigational Site
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Cambridge Brain Mets Trial 1 PHASE1 Proof of principle phase 1b / randomised phase 2 study of afatinib penetrat...
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Cambridge University Hospitals NHS Foundation Trust
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Phase 1/2 Study of MRTX849 in Patients With Cancer Having a KRAS G12C Mutation KRYSTAL-1 PHASE1 This study will evaluate the safety, tolerability, drug levels, molecular e...
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Active Not Recruiting
Location
Local Institution - 001-826
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Sotorasib Activity in Subjects With Advanced Solid Tumors With KRAS p.G12C Mutation (CodeBreak 101) PHASE1 To evaluate the safety and tolerability of sotorasib administered in invest...
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Active Not Recruiting
Location
Arizona Oncology Associates Professional Corporation
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Combining Afatinib and Concurrent Chemotherapy, Followed by Osimertinib and Concurrent Chemotherapy, in Untreated EGFR Positive NSCLC Tumors PHASE2 The aim of the COMBINATION trial is to prospectively study the sequential a...
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Amsterdam UMC, location VUmc
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Study of Furmonertinib in Patients With Advanced or Metastatic Non-Small Cell Lung Cancer (NSCLC) With Activating, Including Uncommon, Epidermal Growth Factor Receptor (EGFR) or Human Epidermal Growth Factor Receptor 2 (HER2) Mutations PHASE1 This is a Phase 1b, open-label, multi-center, dose-escalation and dose expa...
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Active Not Recruiting
Location
ArriVent Investigative Site
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Pemigatinib + Afatinib in Advanced Refractory Solid Tumors PHASE1 This study is researching whether the combination of Afatinib and Pemigatin...
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Massachusetts General Hospital
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A Trial of the Combination of Afatinib and Palbociclib in Previously Treated Advanced Esophageal Squamous Cell Carcinoma PHASE1 The goal of this clinical trial is to learn if Afatinib plus Palbociclib wo...
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West China Hospital
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