Found 57 matching trials
Study of AZD1775 in Combination With Paclitaxel, in Advanced Gastric Adenocarcinoma Patients Harboring TP53 Mutation as a Second-line Chemotherapy PHASE2 This study is a single arm, single center phase II study of AZD1775 in comb...
Show More Location
Samsung Medical center
Learn More & Join Trial
A Placebo Controlled Study Comparing AZD1775+ Docetaxel Versus Placebo+Docetaxel to Treat Lung Cancer PHASE2 A Lead-in Phase II Multicentre, Randomised, Double-Blind Study Comparing AZ...
Show More Learn More & Join Trial
Safety, Tolerance, PK, and Anti-tumour Activity of AZD1775 Monotherapy in Patients With Advanced Solid Tumours PHASE1 This is an open-label, multi-centre, Phase Ib study of AZD1775 designed to ...
Show More Learn More & Join Trial
MPACT Study to Compare Effects of Targeted Drugs on Tumor Gene Variations PHASE2 This phase II trial studies molecular profiling-based assignment of cancer ...
Show More Location
University of Colorado Hospital
Learn More & Join Trial
AZD1775 in Women With Recurrent or Persistent Uterine Serous Carcinoma or Uterine Carcinosarcoma PHASE2 This research study is studying an investigational drug as a possible treat...
Show More Status
Active Not Recruiting
Location
Dana Farber Cancer Institute
Learn More & Join Trial
Testing the Sequential Combination of the Anti-cancer Drugs Olaparib Followed by Adavosertib (AZD1775) in Patients With Advanced Solid Tumors With Selected Mutations and PARP Resistance, STAR Study PHASE1 This phase I trial studies the side effects and best dose of adavosertib wh...
Show More Status
Active Not Recruiting
Location
UT MD Anderson Cancer Center
Learn More & Join Trial
A Study of Adavosertib as Treatment for Uterine Serous Carcinoma PHASE2 This Phase 2b study aims to evaluate the efficacy and safety of adavosertib...
Show More Learn More & Join Trial
Study With Wee-1 Inhibitor AZD1775 (MK-1775) and Carboplatin to Treat p53 Mutated Refractory and Resistant Ovarian Cancer PHASE2 The purpose of this study is to determine if patients with p53 mutated epit...
Show More Learn More & Join Trial
A Dose Escalation Study of Adavosertib(MK1775) in Combination With 5-FU or 5-FU/CDDP in Patients With Advanced Solid Tumor (1775-005 PHASE1 The study evaluates safety of adavosertib in monotherapy, and in combinatio...
Show More Location
Multiple Locations
Learn More & Join Trial
Phase II, Single-arm Study of AZD1775 Monotherapy in Relapsed Small Cell Lung Cancer Patients With MYC Family Amplification or CDKN2A Mutation Combined With TP53 Mutation PHASE2 AZD1775 (previously known as MK-1775 in earlier studies) is an inhibitor of...
Show More Learn More & Join Trial