Found 29 matching trials
Safety and Efficacy of Intra-Arterial and Intra-Tumoral Ad-p53 With Capecitabine (Xeloda) or Anti-PD-1 in Liver Metastases of Solid Tumors and Recurrent Head and Neck Squamous Cell Cancer PHASE1 This is a Phase 1/2 study of the combination of Ad-p53 administered intra-a...
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MD Anderson Cancer Center
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Gene Therapy in Treating Patients With Recurrent Malignant Gliomas PHASE1 RATIONALE: Inserting the gene for adenovirus p53 into a person's tumor may ...
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UCSF Cancer Center and Cancer Research Institute
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Neoadjuvant/Adjuvant Chemotherapy, Vaccine & Adjuvant Radiation Therapy in p53-Overexpressing Stage III Breast Cancer PHASE1 RATIONALE: Vaccines may make the body build an immune response to kill tumo...
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Eppley Cancer Center, University of Nebraska Medical Center
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Gene Therapy in Treating Patients With Cancer of The Liver PHASE1 Phase I trial to study the effectiveness of gene therapy with the p53 gene ...
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Albert Einstein Comprehensive Cancer Center
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Gene Therapy in Treating Patients With Advanced Recurrent or Persistent Ovarian Cancer or Primary Peritoneal Cancer PHASE1 RATIONALE: Inserting the p53 gene into a person's cancer cells may improve ...
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Simmons Cancer Center - Dallas
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Chemotherapy Combined With Gene Therapy in Treating Patients Who Have Stage III or Stage IV Breast Cancer PHASE2 RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cell...
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University of Texas - MD Anderson Cancer Center
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Gene Therapy in Treating Patients With Non-small Cell Lung Cancer That Cannot Be Surgically Removed PHASE1 RATIONALE: Exposing tumor cells to the p53 gene may improve the body's abil...
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Veterans Affairs Medical Center - Tennessee Valley Healthcare System - Nashville Campus
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AD 32 With or Without BCG After Surgery in Treating Patients With Newly Diagnosed or Recurrent Superficial Bladder Cancer PHASE2 RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cell...
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University of Texas - MD Anderson Cancer Center
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SCH-58500 in Treating Patients With Primary Ovarian, Fallopian Tube, or Peritoneal Cancer (C95084) PHASE1 RATIONALE: Giving the p53 gene for ovarian, fallopian tube, or peritoneal c...
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Multiple Locations
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Autologous SCT Followed by Dendritic Cell p53 Vaccination in Patients With Limited Stage Small Cell Lung Cancer PHASE2 The purpose of this study is to determine whether p53 vaccination followed ...
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