Found 131 matching trials
SAFIR02_Lung - Efficacy of Targeted Drugs Guided by Genomic Profiles in Metastatic NSCLC Patients PHASE2 Open label multicentric randomized phase II trial, using high throughput ge...
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Centre Hospitalier Henri Duffau
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Study of Selumetinib (MK-5618) in Combination With Pembrolizumab (MK-3475) in Participants With Advanced/Metastatic Solid Tumors (MK-5618-001) PHASE1 This study will examine the safety, pharmacokinetics, and efficacy of escal...
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City of Hope National Medical Center ( Site 0004)
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AZD6244 With Cetuximab for Solid Tumors and Colorectal Cancer PHASE1 Background:
\- The experimental cancer treatment drug AZD6244 has been sho...
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National Institutes of Health Clinical Center, 9000 Rockville Pike
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To Assess the Pharmacokinetics, Safety and Tolerability of Selumetinib in Patients With Hepatic Impairment and Healthy Subjects PHASE1 A study to assess the pharmacokinetics, safety and tolerability of Selumeti...
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AZD6244 (ARRY-142886) Solid Oral Dosage Formulation in Participants With Advanced Solid Malignancies PHASE1 The primary purpose of the study is to assess the safety, tolerability and ...
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Active Not Recruiting
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Molecular Profiling and Targeted Therapy for Advanced Non-Small Cell Lung Cancer, Small Cell Lung Cancer, and Thymic Malignancies PHASE2 Background:
\- The current standard of care for advanced lung cancer and c...
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National Institutes of Health Clinical Center
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Selumetinib Sulfate in Treating Woman With Recurrent Low-Grade Ovarian Cancer or Peritoneum Cancer PHASE2 This phase II trial studies the side effects and how well selumetinib sulfa...
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USC / Norris Comprehensive Cancer Center
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Selumetinib With or Without Temsirolimus in Treating Patients With Metastatic, Recurrent, or Locally Advanced Soft Tissue Sarcoma That Cannot Be Removed By Surgery PHASE2 This randomized phase II trial is studying how well giving selumetinib toge...
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Tower Cancer Research Foundation
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Randomised Study to Compare the Efficacy of AZD6244 vs TMZ PHASE2 The primary purpose of this study is to compare the efficacy of AZD6244 (AR...
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To Assess the Effects of Single Oral Dose of Selumetinib [AZD6244; ARRY-142886] [Hyd-Sulfate]), on QTc Interval in Healthy Male Volunteers PHASE1 Study to assess the effect of Selumetinib \[AZD6244; ARRY-142886\] \[Hyd-Su...
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