Found 38 matching trials
SAFIR02_Lung - Efficacy of Targeted Drugs Guided by Genomic Profiles in Metastatic NSCLC Patients PHASE2 Open label multicentric randomized phase II trial, using high throughput ge...
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Centre Hospitalier Henri Duffau
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Fulvestrant +/- Akt Inhibition in Advanced Aromatase Inhibitor Resistant Breast Cancer PHASE1 This is a two stage study, with an initial dose escalation phase I study an...
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Active Not Recruiting
Location
Velindre NHS Trust
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Phase I Study of AZD5363 + Olaparib + Durvalumab in Patients With Advanced or Metastatic Solid Tumor Malignancies PHASE1 This is a Phase 1 dose-escalation study to evaluate the safety and tolerabi...
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National University Hospital
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Study of AZD5363 in Combination With Paclitaxel, in Advanced Gastric Adenocarcinoma Patients Harboring PIK3CA Mutation and/or PIK3CA Amplification as a Second-line Chemotherapy PHASE2 This study is a single arm, single center phase II study of AZD5363 in comb...
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Samsung Medical Center
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A Study of Novel Anti-cancer Agents in Patients With Metastatic Triple Negative Breast Cancer PHASE1 This study is designed to determine the efficacy and safety of durvalumab i...
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Active Not Recruiting
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mTORC1/2 Inhibitor AZD2014 or the Oral AKT Inhibitor AZD5363 for Recurrent Endometrial and Ovarian PHASE1 This phase Ib/II trial studies the side effects and best dose of olaparib a...
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Location
M D Anderson Cancer Center
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A Phase I Study to Investigate the Pharmacokinetics and Safety of Capivasertib in Participants With Moderate Hepatic Impairment PHASE1 The purpose of this study is to measure the pharmacokinetics (PK), safety, ...
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IACS-6274 With or Without Bevacizumab and Paclitaxel for the Treatment of Advanced Solid Tumors PHASE1 To find the highest tolerable dose of IACS-6274 that can be given alone, in...
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M D Anderson Cancer Center
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AMTEC IIT: Phase 2 Multiarm Study in TNBC PHASE2 This phase II study assesses the efficacy of the combination of olaparib wi...
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OHSU Knight Cancer Institute
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National Lung Matrix Trial: Multi-drug Phase II Trial in Non-Small Cell Lung Cancer PHASE2 The trial consists of a series of parallel multi-centre single arm phase II...
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Aberdeen Royal Infirmary
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