Found 16 matching trials
Drug-drug Interaction Study With AZD5305 and Itraconazole in Patients With Advanced Solid Malignancies
PHASE1This study is a single-arm, open-label, multi-centre drug-drug interaction ...
AZD5305 hADME in Patients With Advanced Solid Malignancies
PHASE1This Phase I, open-label study aims to study to absolute bioavailability of...
Phase I/IIa Study of AZD5335 as Monotherapy and Combination Therapy in Participants With Solid Tumors
PHASE1This research is designed to determine if experimental treatment with Antib...
Study of AZD5305 When Given in Combination With New Hormonal Agents in Patients With Metastatic Prostate Cancer
PHASE1This study will evaluate the safety, tolerability, pharmacokinetics (PK), p...
Status
Active Not Recruiting
A Platform Study of Novel Agents in Combination With Radiotherapy in NSCLC
PHASE1CONCORDE is a multi-institution, multi-arm, Phase IB study that will determ...
Location
Belfast City Hospital
Ascending Doses of Ceralasertib in Combination With Chemotherapy and/or Novel Anti Cancer Agents
PHASE1This is a modular, phase I/ phase 1 b, open-label, multicentre study of cer...
Status
Active Not Recruiting
Targeted Pathway Inhibition in Patients With Pancreatic Cancer
EARLY_PHASE1This early phase I trial aims to determine how cobimetinib, olaparib, onvan...
Location
OHSU Knight Cancer Institute
Saruparib (AZD5305) vs Placebo in Men With Metastatic Castration-Sensitive Prostate Cancer Receiving Physician's Choice New Hormonal Agents
PHASE3The intention of the study is to demonstrate superiority of Saruparib (AZD5...
Status
Active Not Recruiting
A Phase I/IIa Study of AZD8205 Given Alone or Combined, in Participants With Advanced/Metastatic Solid Malignancies
PHASE1This research study is studying a new compound, AZD8205, as a possible trea...
A Study of Metastases Free Survival With Saruparib vs Placebo Added to a Standard RT/ADT in Men With High-risk Prostate Cancer With a BRCA Mutation
PHASE3The purpose of the study is to demonstrate superiority of Saruparib (AZD530...