Found 14 matching trials
A Study in Participants With Non-cirrhotic NASH With Fibrosis
PHASE2This is a randomized, double-blind, placebo-controlled, parallel-group, mul...
A Phase I, Safety Tolerability and Pharmacokinetics of AZD4831 to Treat Cardiovascular Disease
PHASE1This is a Phase I study to investigate the safety and tolerability of AZD48...
A Study to Assess the Safety and Tolerability of Single and Multiple Doses of AZD4831 in Healthy Male Subjects
PHASE1This is a Phase I, first-in-human (FIH) study to assess the safety, tolerab...
Location
Multiple Locations
A Study to Assess the Mass Balance Recovery, Pharmacokinetics, Metabolite Profile and Metabolite Identification of [14C]AZD4831
PHASE1The Sponsor is developing the test medicine, AZD4831, for the potential tre...
A Study to Assess the Effect AZD4831 in Japanese and Chinese Healthy Volunteers
PHASE1This study is randomized, single-blind, placebo-controlled Phase 1 study ai...
Study to Assess the Effect of AZD4831 on the Pharmacokinetics (Drug Behavior in the Body) of Midazolam
PHASE1The study is an open-label, fixed-sequence, cross-over study conducted at a...
Myeloperoxidase (MPO) Inhibitor A_Zeneca for Heart Failure With Preserved Ejection Fraction (HFpEF)
PHASE1Researchers are studying the effect of a single dose of oral myeloperoxidas...
Location
Mayo Clinic in Rochester
An Efficacy and Safety Study of Mitiperstat (AZD4831) (MPO Inhibitor) vs Placebo in the Treatment of Moderate to Severe COPD.
PHASE2This is a research study to evaluate the efficacy and safety of the investi...
A Study to Assess the Relative Bioavailability and Safety of Different Formulations of AZD4831 in Fasted State in Healthy Volunteers.
PHASE1A study to assess the relative bioavailability and safety of different form...
Safety and Tolerability Study of AZD4831 in Patients With Heart Failure.
PHASE2A randomized, double-blind, placebo-controlled, parallel group, multicentre...