Found 26 matching trials
A Study of Rilvegostomig or Durvalumab Plus Chemotherapy for First-Line Treatment of Biliary Tract Cancer (ARTEMIDE-Biliary02) PHASE3 The purpose of this study is to measure the efficacy and safety of rilvegos...
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Ph1b/2 Study of the Safety and Efficacy of T-DXd Combinations in Advanced HER2-expressing Gastric Cancer (DESTINY-Gastric03) PHASE2 DESTINY-Gastric03 will investigate the safety, tolerability, pharmacokineti...
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A Study of Novel Anti-cancer Agents in Patients With Previously Untreated NSCLC PHASE1 This study is designed to determine the efficacy and safety of durvalumab a...
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Sonesitatug Vedotin in Combination With Capecitabine With or Without Rilvegostomig in Participants With Advanced or Metastatic Gastric, Gastroesophageal Junction, or Esophageal Adenocarcinoma Expressing Claudin18.2 PHASE3 The purpose of this study is to evaluate the efficacy and safety of sonesit...
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Phase Ib Study of the Safety of T-DXd and Immunotherapy Agents With and Without Chemotherapy in Advanced or Metastatic HER2+, Non-squamous NSCLC PHASE1 DESTINY-Lung03 will investigate the safety and tolerability of trastuzumab ...
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A Study to Investigate the Pharmacokinetics and Safety of Subcutaneous Rilvegostomig in Adult Participants With Advanced Solid Tumors Previously Treated With Standard of Care Therapy PHASE1 The purpose of this study is to determine the subcutaneous (SC) dose that g...
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Phase 1b Study of Dato-DXd in Combination With Immunotherapy With or Without Carboplatin in Advanced or Metastatic Non-Small Cell Lung Cancer PHASE1 This study will assess safety, tolerability, and treatment activity of dato...
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A Phase I/IIa Study of AZD8205 Given Alone or Combined, in Participants With Advanced/Metastatic Solid Malignancies PHASE1 This research study is studying a new compound, AZD8205, as a possible trea...
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A Study of Novel Agents or Combinations as Perioperative Treatment in Participants With Locally Advanced Resectable Gastroesophageal Adenocarcinoma PHASE2 GEMINI-PeriOp GC study will assess the safety, tolerability, pharmacokineti...
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An Open-label Study to Investigate the Efficacy and Safety of Dato-DXd + Rilvegostomig vs SoC in Adult Participants With High-risk MIUC PHASE3 Purpose: to assess efficacy and safety of Dato-DXd + rilvegostomig as adjuv...
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