Found 8 matching trials
A Study to Evaluate the Safety, Tolerability, PK, and PD Effects of AZD2389 in Participants With Liver Fibrosis and Compensated Cirrhosis. PHASE2 The purpose of this study is to measure the safety, tolerability, and the w...
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A Study to Investigate How Multiple Oral Doses of AZD2389 Affect the Pharmacokinetics of Midazolam, Caffeine, and Bupropion in Healthy Participants PHASE1 The purpose of this study is to measure the effect of multiple doses of AZD...
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A Study to Investigate the Pharmacokinetics of AZD2389 When Administered Alone and in Combination With Itraconazole in Healthy Participants PHASE1 The purpose of this study is to assess the pharmacokinetics (PK) of AZD2389...
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The Phase 1, Open-label, PET Trial Designed to Investigate the Effect of AZD2389 on FAP Occupancy in the Liver in Participants With Advanced Liver Fibrosis. PHASE1 This is a phase 1, open-label, PET trial. The study is designed to investig...
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A Study to Investigate the Pharmacokinetics of AZD2389 in Healthy Participants When Administered Alone and in Combination With Quinidine PHASE1 The purpose of this study is to assess the pharmacokinetics (PK) and safety...
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A Single and Multiple Ascending Dose Study to Investigate Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of AZD2389 in Healthy Participants PHASE1 This study will assess the safety, tolerability, pharmacokinetics (PK), and...
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Study of AZD2389 Safety, Tolerability, and Pharmacodynamics in Adults With Steatotic Liver Disease and Advanced Fibrosis PHASE2 The purpose of this study is to evaluate the safety, tolerability, and phar...
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A Study to Investigate the Effect of Hepatic Impairment on the Pharmacokinetics, Safety, and Tolerability of AZD2389 PHASE1 The purpose of this study is to examine the safety and tolerability of AZD2...
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