Found 58 matching trials
Study of AZD1775 in Combination With Paclitaxel, in Advanced Gastric Adenocarcinoma Patients Harboring TP53 Mutation as a Second-line Chemotherapy PHASE2 This study is a single arm, single center phase II study of AZD1775 in comb...
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Samsung Medical center
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A Placebo Controlled Study Comparing AZD1775+ Docetaxel Versus Placebo+Docetaxel to Treat Lung Cancer PHASE2 A Lead-in Phase II Multicentre, Randomised, Double-Blind Study Comparing AZ...
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Safety, Tolerance, PK, and Anti-tumour Activity of AZD1775 Monotherapy in Patients With Advanced Solid Tumours PHASE1 This is an open-label, multi-centre, Phase Ib study of AZD1775 designed to ...
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Phase I Study to Assess the Effect of Food on AZD1775 Pharmacokinetics in Patients With Advanced Solid Tumours PHASE1 The purpose of this study is to assess the effect of food on the pharmacoki...
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MPACT Study to Compare Effects of Targeted Drugs on Tumor Gene Variations PHASE2 This phase II trial studies molecular profiling-based assignment of cancer ...
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University of Colorado Hospital
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AZD1775 in Women With Recurrent or Persistent Uterine Serous Carcinoma or Uterine Carcinosarcoma PHASE2 This research study is studying an investigational drug as a possible treat...
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Active Not Recruiting
Location
Dana Farber Cancer Institute
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Testing the Sequential Combination of the Anti-cancer Drugs Olaparib Followed by Adavosertib (AZD1775) in Patients With Advanced Solid Tumors With Selected Mutations and PARP Resistance, STAR Study PHASE1 This phase I trial studies the side effects and best dose of adavosertib wh...
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Active Not Recruiting
Location
UT MD Anderson Cancer Center
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A Study of Adavosertib as Treatment for Uterine Serous Carcinoma PHASE2 This Phase 2b study aims to evaluate the efficacy and safety of adavosertib...
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Study With Wee-1 Inhibitor AZD1775 (MK-1775) and Carboplatin to Treat p53 Mutated Refractory and Resistant Ovarian Cancer PHASE2 The purpose of this study is to determine if patients with p53 mutated epit...
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AZD1775 Continued Access Study to Assess Safety and Tolerability for Patients Enrolled in AZD1775 Clinical Pharmacology Studies PHASE1 Open-label, non-randomised study to provide continued access to AZD1775 for...
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