Found 8 matching trials
A Trial of Aclaris Therapeutics, Inc. (ATI)-450 in Patients With Moderate-severe Novel Coronavirus Disease 2019 (COVID-19) PHASE2 COVID-19 morbidity and mortality has been associated with Cytokine Release ...
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The University of Kansas Medical Center
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ATI-450 vs Placebo in Participants With Moderate to Severe Hidradenitis Suppurativa (HS) PHASE2 This is a Phase 2a study to investigate the efficacy, safety, tolerability,...
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Aclaris Investigational Site
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MK2 Inhibitor in Combination With mFOLFIRINOX for Untreated Metastatic Pancreatic Ductal Adenocarcinoma PHASE1 The investigators hypothesize that MK2 inhibition may improve efficacy of m...
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Washington University School of Medicine
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ATI-450 Plus Methotrexate (MTX) Versus Placebo Plus MTX in Participants With Moderate to Severe Active Rheumatoid Arthritis (RA) PHASE2 This study evaluates ATI-450 plus MTX versus placebo plus MTX in participan...
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Aclaris Investigational Site
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Study of ATI-450 vs Placebo in Patients With Moderate to Severe Psoriatic Arthritis PHASE2 This is a Phase 2a study to investigate the efficacy, safety, tolerability,...
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Aclaris Investigational Site
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Study of ATI-450 in Patients With Cryopyrin-Associated Periodic Syndrome (CAPS) PHASE2 This is a Phase 2 study to investigate the safety and efficacy of ATI-450 f...
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Aclaris Investigational Site
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Study of ATI-450 Plus Methotrexate (MTX) vs MTX Alone in Patients With Moderate to Severe RA PHASE2 This is a Phase 2 study to investigate the safety, tolerability, PK, and PD...
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Aclaris Investigational Site
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Zunsemetinib in Combination With Capecitabine in Patients With Hormone Receptor-Positive and HER2-Negative Metastatic Breast Cancer With Bone Metastasis PHASE1 This is a phase Ib/II study evaluating the safety and efficacy of zunsemeti...
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The University of Kansas Cancer Center
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