Found 10 matching trials
A Drug-Drug Interaction Study of CYP3A4 Inhibition and Pan-CYP Induction on APX001
PHASE1This is a Phase 1, open-label study to evaluate the drug-drug interaction p...
Location
PRA Health Sciences (PRA) - Early Development Services (EDS)
Safety, Pharmacokinetics, Bioavailability, Food Effect, Drug-Drug Interaction Study of APX001 Administered Orally
PHASE1This is a Phase l double-blind, placebo-controlled, randomized study to inv...
Location
PRA Health Sciences (PRA) - Early Development Services (EDS)
Study to Assess Safety, Tolerability and Pharmacokinetics of APX001 Administered by Intravenous Infusion to Healthy Subjects
PHASE1First In Human (FIH), randomized, double-blind, placebo-controlled single a...
Location
PRA Health Sciences
An Open-label Study of APX001 for Treatment of Patients With Candidemia/Invasive Candidiasis Caused by Candida Auris
PHASE2This is a multicenter, open-label, single arm study to evaluate the efficac...
Location
Netcare Union Hospital Trauma Surgeons
A Study to Assess the Mass Balance Recovery and Metabolite Profile & Identification of [14C]-APX001 in Healthy Males
PHASE1This is a single-center, open-label, non-randomized, single dose study in h...
Location
Quotient Sciences
Safety and Pharmacokinetics of Intravenous and Oral APX001 in Patients With Acute Myeloid Leukemia (AML) and Neutropenia
PHASE1An open-label, multi-center, Phase Ib study to determine the safety and pha...
Location
University of Cologne, Center for Integrated Oncology (CIO)
A Bioequivalence Study of APX001 High-load and Low-load Tablets
PHASE1A study to learn about the bioequivalence (the biochemical similarity of tw...
Location
Pharmaceuticals Research Associates, Inc
A Clinical Trial of the Study Medicine (Called Fosmanogepix) in Participants With Varying Degrees of Hepatic Function.
PHASE1The primary purpose of this open-label study is to characterize the plasma ...
Location
Inland Empire Liver Foundation
An Efficacy and Safety Study of APX001 in Non-Neutropenic Patients With Candidemia
PHASE2This is a multicenter, open-label, non-comparative, single-arm study to eva...
Location
University of Alabama at Birmingham School of Medicine
Open-label Study of APX001 for Treatment of Patients With Invasive Mold Infections Caused by Aspergillus or Rare Molds
PHASE2This is a Phase 2, multicenter study to evaluate APX001 for the treatment o...
Location
City of Hope (City of Hope National Medical Center, City of Hope Medical Center)