Found 13 matching trials
APR-246 in Combination With Azacitidine for TP53 Mutated AML (Acute Myeloid Leukemia) or MDS (Myelodysplastic Syndromes) Following Allogeneic Stem Cell Transplant PHASE2 A multi-center, open label, Phase II clinical trial to assess the safety an...
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H. Lee Moffitt Cancer Center & Research Institute
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APR-246 in Combination With Acalabrutinib or Venetoclax Based Therapy in Subjects With R/R Non Hodgkin Lymphomas (NHL) PHASE1 Study to determine the preliminary safety, tolerability, and pharmacokineti...
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Massachusetts General Hospital
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A Study of APR-246 in Combination With Dabrafenib in Resistant Patients With BRAF V600 Mutant Melanoma PHASE1 The purpose of this study is to make a preliminary assessment of the effica...
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Institut Jules Bordet
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Study of the Safety and Efficacy of APR-246 in Combination With Azacitidine PHASE1 The main purpose of this study is to determine the safe and efficacy of APR...
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Venetoclax and Eprenetapopt for the Treatment of Relapsed of Refractory Mantle Cell Lymphoma PHASE2 This phase II trial investigates the effect of venetoclax and eprenetapopt ...
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M D Anderson Cancer Center
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APR-246 in Combination With Venetoclax and Azacitidine in TP53-Mutant Myeloid Malignancies PHASE1 This clinical trial is a Phase I, open-label, dose-finding and cohort expan...
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Yale Cancer Center
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Phase 1b/2 Safety and Efficacy of APR-246 w/Azacitidine for tx of TP53 Mutant Myeloid Neoplasms PHASE1 The main purpose of this study is to determine the safe and recommended dos...
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H. Lee Moffitt Cancer Center and Research Institute
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p53 Suppressor Activation in Recurrent High Grade Serous Ovarian Cancer, a Phase Ib/II Study of Systemic Carboplatin Combination Chemotherapy With or Without APR-246 PHASE1 The purpose of this study is to make a preliminary assessment of the effica...
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p53 Activation in Platinum-Resistant High Grade Serous Ovarian Cancer, a Study of PLD With APR-246 PHASE2 The purpose of this study is to make a preliminary assessment of the effica...
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Medische oncologie, Universitair Ziekenhuis Gent
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Safety Study of APR-246 in Patients With Refractory Hematologic Cancer or Prostate Cancer PHASE1 The purpose of this study is to determine the highest feasible dose (HFD) o...
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Section of Haematology and Coagulation, Sahlgrenska University Hospital
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