Found 9 matching trials
APG-1252 Monotherapy or in Combination With Other Therapeutic Agent in Subjects With Relapsed or Refractory Non-Hodgkin Lymphoma
PHASE1The purpose of this study is to assess the safety, pharmacokinetic, pharmac...
Location
Henan Provincial Oncology Hospital
A Study of Pelcitoclax (APG-1252) in Patients With Neuroendocrine Tumors
PHASE1APG-1252 is a highly potent Bcl-2 family protein inhibitor, a promising dru...
Location
The First Affiliated Hospital of Sun Yat-Sen University
Study of APG-1252 Plus Paclitaxel in Patients With Relapsed/Refractory Small Cell Lung Cancer
PHASE1This is a multi-center, open-label, phase Ib/II study of combination therap...
Location
BRCR Medical Center
A Study of APG-1252 in Patients With SCLC or Other Solid Tumors
PHASE1APG-1252 is a highly potent Bcl-2 family protein inhibitor, a promising dru...
A Study of APG-1252 in Patients With Myelofibrosis Who Progressed After Initial Therapy
PHASE1The study is a designed to evaluate safety and activity of APG-1252 when ad...
Location
Banner MD Anderson Cancer Center
APG-1252 in Patients With SCLC or Advanced Solid Tumors
PHASE1APG-1252 is a highly potent Bcl-2 family protein inhibitor, a promising dru...
Location
Guangdong General Hospital
A Study of APG-1252 Plus Osimertinib(AZD9291) in EGFR TKI Resistant NSCLC Patients
PHASE1There are unmet medical needs in patients who resist to EGFR TKIs, especial...
Status
Active Not Recruiting
Location
Sun-Yat Sen University Cancer Center
Testing the Combination of APG-1252 (Pelcitoclax) and Cobimetinib in Recurrent Ovarian and Endometrial Cancers
PHASE1This phase I trial tests the safety, side effects, and best dose of combina...
Status
Active Not Recruiting
Location
Emory University Hospital/Winship Cancer Institute
Phase1b/2 Trial Of AZA + APG1252 In Patients With High-Risk AML
PHASE1This is a phase Ib/II study that aims to investigate the safety, tolerabili...