Found 18 matching trials
Brodalumab Drug-Drug Interaction (DDI) and Intensive Pharmacodynamic (PK) Study in Psoriasis Subjects
PHASE1This is a phase 1, multi-center, open-label, drug-drug interaction (DDI) an...
Safety and Efficacy of AMG 827 in Subjects With RA
PHASE2This is an extension study for subjects who participated in Protocol 200900...
Efficacy, Safety, and Withdrawal and Retreatment With Brodalumab in Moderate to Severe Plaque Psoriasis Subjects
PHASE3The purpose of this study is to assess the safety and efficacy of brodaluma...
Study to Evaluate the Safety, PK, PD and Efficacy of AMG 827 in Adults With Rheumatoid Arthritis
PHASE1This Phase 1b/2a study will evaluate safety, tolerability pharmacokinetics ...
Location
Multiple Locations
P3 Study Brodalumab in Treatment of Moderate to Severe Plaque Psoriasis
PHASE3The purpose of this study is to assess the safety and efficacy of brodaluma...
Study to Evaluate the Safety, Tolerability, and Efficacy of AMG 827 in Subjects With Psoriasis
PHASE2The study evaluated the efficacy of AMG 827 compared with placebo as measur...
Location
Multiple Locations
Study of Efficacy, Safety and Effect on Radiographic Progression of Brodalumab in Subjects With Psoriatic Arthritis
PHASE3The primary objective of this study is to evaluate the efficacy of brodalum...
Single-Dose Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of AMG 827
PHASE1This Phase 1 study will evaluate safety, tolerability, PK and PD of AMG 827...
Location
Multiple Locations
Study of Efficacy and Safety of Brodalumab Compared With Placebo in Adults With Inadequately Controlled Asthma With High Bronchodilator Reversibility
PHASE2The purpose of this study is to determine if brodalumab (AMG 827) is safe a...
Study of Efficacy and Safety of Brodalumab in Subjects With Psoriatic Arthritis
PHASE3The primary objective of this study is to evaluate the efficacy of brodalum...