Found 15 matching trials
Copper Concentration & Histopathologic Changes in Liver Biopsy in Participants With Wilson Disease Treated With ALXN1840
PHASE2The main objective of the study is to evaluate the change in liver copper (...
Copper Balance in Healthy Participants Administered ALXN1840
PHASE1The study will assess the change from baseline in mean daily copper balance...
Location
Clinical Study Site
Study of ALXN1840 on the Metabolism of a CYP2B6 Substrate in Healthy Participants
PHASE1This is a Phase 1, randomized, 2-period, 2-sequence, cross-over study desig...
Location
Clinical Trial Site
Early Access Program for ALXN1840 in Patients With Wilson Disease
N/AThis is an open-label, single-arm, multi-center EAP, designed to provide ea...
Status
No Longer Available
Location
Multiple Locations
Copper and Molybdenum Balance in Participants With Wilson Disease Treated With ALXN1840
PHASE2This exploratory study will investigate the effects of ALXN1840 on copper b...
Efficacy and Safety Study of WTX101 (ALXN1840) in Adult Wilson Disease Patients
PHASE2The main purpose of the study was to evaluate the efficacy of ALXN1840 (for...
Location
Clinical Trial Site
Bioavailability Study of 2 Oral Formulations of ALXN1840
PHASE1The study will assess the relative bioavailability of 2 different formulati...
Location
Nucleus Network Pty Ltd.
A Study of the Cardiac Effects of ALXN1840 in Healthy Adults
PHASE1This study will evaluate the effect of a supratherapeutic dose of ALXN1840 ...
Location
PPD Development, LP
A Study of ALXN1840 (Coated and Non-coated) Administered With And Without Omeprazole In Healthy Adults
PHASE1This was single-center, open-label, randomized, 3-period, 3-treatment, 6-se...
Location
Clinical Trial Site
A Study of ALXN1840 (Non-coated) Administered With And Without Omeprazole In Healthy Adults
PHASE1This was single-center, open-label, randomized, 3-period, 3-treatment, 6-se...
Location
Clinical Trial Site