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Study to Evaluate Safety, Tolerability and Efficacy of Inclisiran in Children With Homozygous Familial Hypercholesterolemia PHASE3 This is a pivotal phase III study designed to evaluate safety, tolerability...
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UC San Francisco Medical Center
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A Phase 1 Study of an Investigational Drug, ALN-PCSSC, in Subjects With Elevated Low Density Lipoprotein Cholesterol (LDL-C) PHASE1 The purpose of this study is to evaluate the safety, tolerability, pharmaco...
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Covance Clinical Research Unit
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Multicenter Real-World Cohort Study Evaluating the Impact of Early Intensive Lipid-Lowering Therapy on the Prognosis of Acute Coronary Syndrome Patients(ELITE-ACS) N/A The purpose of this clinical trial is to evaluate the impact of early initi...
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Chinese PLA General Hospital
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A Randomized Trial Assessing the Effects of Inclisiran on Clinical Outcomes Among People With Cardiovascular Disease PHASE3 ORION-4 is a research study coordinated by the University of Oxford and co-...
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Active Not Recruiting
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Trial to Assess the Effect of Long Term Dosing of Inclisiran in Subjects With High CV Risk and Elevated LDL-C PHASE3 The purpose of this extension study was to evaluate the efficacy, safety, a...
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Research Site 10001-015
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Inclisiran for Subjects With ASCVD or ASCVD-Risk Equivalents and Elevated Low-density Lipoprotein Cholesterol PHASE3 This is a Phase III, placebo-controlled, double-blind, randomized study in ...
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Research Site 11420-002
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PET Imaging of Inflammation and Lipid Lowering Study NA While 18F-fluorodeoxyglucose (FDG) positron emission tomography (PET) imagi...
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University of Cambridge
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Inclisiran (Leqvio®) in Patients With Atherosclerotic Vascular Disease and/or Heterozygous Familial Hypercholesterolemia Treated in Spain: the INSPIRE Study N/A This study aims to address several key questions regarding the use of incli...
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Location
Novartis Investigative Site
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Impact of Optimal Pharmacotherapy on Lipid Profile and Qualitative Features of Atherosclerotic Plaques N/A Lipid accumulation, with mostly emphasized role of low-density lipoprotein ...
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Pauls Stradins Clinical University Hospital
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A Study to Investigate LDL-cholesterol Lowering With Inclisiran Compared to Bempedoic Acid in Patients With Atherosclerotic Cardiovascular Disease. PHASE4 This study is a phase IV, open-label, randomized study designed to evaluate...
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Novartis Investigative Site
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