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AK117 (Anti-CD47 mAb) Plus Cetuximab or AK104 (Anti-PD-1/CTLA-4 bsAb) as Second-Line Therapy in Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma PHASE2 The administration of first-line pembrolizumab monotherapy or combined chem...
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Active Not Recruiting
Location
West China Hospital, Sichuan University
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A Phase 3 Study of AK112 Plus AK117 Versus Pembrolizumab in Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma (R/M HNSCC) PHASE3 This is a phase 3 study. All subjects arerecurrent or metastatic head and n...
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Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
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A Study of AK117 in Combination With Azacitidine in Patients With Myelodysplastic Syndromes PHASE2 This is a Phase 2 randomized, double-blind, placebo-controlled, multicenter...
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UCLA Ronald Reagan Medical Center
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A Study of AK112 in Advanced Malignant Tumors PHASE1 Phase Ib/II open label, multicenter study to evaluate the efficacy and safe...
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Zhejiang Cancer Hospital
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A Study of AK117 in Combination With Azactidine Plus Venetoclax in Patients With Acute Myeloid Leukemia PHASE1 This is a phase 1b/2 study. All patients are diagnosed with Acute Myeloid L...
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Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College
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A Study of AK112 With or Without AK117 in Metastatic Colorectal Cancer PHASE2 This trial is a Phase II study. The purpose of this study is to evaluate th...
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Active Not Recruiting
Location
Summit Therapeutics Research Site
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Study Comparing Ivonescimab Alone or Ivonescimab in Combination With Ligufalimab Versus Pembrolizumab for the Treatment of SCCHN PHASE3 This is a randomized, open-label, active-comparator-controlled, multi-regio...
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Centre Guillaume Le Conquerant
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A Phase III Study of Ivonescimab + Chemo With/Without AK117 in Metastatic Pancreatic Cancer PHASE3 This is a Phase 3, randomized, double-blind clinical trial aimed at evaluat...
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Harbin Medical University Cancer Hospital
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A Phase Ib/II Study of AK104 and AK117 in Combination With or Without Chemotherapy in Advanced Malignant Tumors PHASE1 Phase Ib/II open label, multicenter study to evaluate the efficacy and safe...
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Shanghai Renji Hospital
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